Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NMT1_HUMAN
Description:N-myristoyltransferase 1 [Source:HGNC Symbol;Acc:7857]
Location:chr17 q21.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S83PVKMNsLPAERNST1PhosphoSitePlus
T52SPANDtGAKKKNST1PhosphoSitePlus
Y180LLNENyVEDDDFynphosphoELM; RegPhos
Y180LLNENyVEDDDFYNHPRD; RegPhos
T427FYNVHtQTPLLNMT_C; Acetyltransf_3PhosphoSitePlus
T71EKGSEtDSAQDNST1PhosphoSitePlus
Y180LLNENyVEDDDLYNHPRD; RegPhos
S31GHEHCsDCENERegPhos
Y180LLNENyVEDDDLynphosphoELM; RegPhos
T343LRPMEtKDIPVNMT_C; Acetyltransf_3PhosphoSitePlus
T319LSRNMtMQRTMNMT_CPhosphoSitePlus
Y180LLNENyVEDDDNMTPhosphoSitePlus
Y117ASKRSyQFWDTLynphosphoELM; RegPhos
S47NRGGLsPANDTHPRD; phosphoELM; RegPhos; SysPTM
S47NRGGLsPANDTNST1PhosphoSitePlus; SysPTM

Dephosphorylation site
NMT1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000258960Y476CBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000258960Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
NMT1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
LYN_HUMANNMT1_HUMANkinase -> substrateHPRD; RegPhos; Robert H Newman (2013)
ZAGL2_HUMANNMT1_HUMANkinase -> substrateRegPhos
FYN_HUMANNMT1_HUMANkinase -> substrateHPRD; RegPhos; Robert H Newman (2013)

Function Annotation
KEGG Pathway
NMT1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004379glycylpeptide N-tetradecanoyltransferase activityIEAmolecular_function
GO:0006498N-terminal protein lipidationNASbiological_process
GO:0016032viral reproductionTASbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0015629actin cytoskeletonIDAcellular_component
GO:0009249protein lipoylationTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0005829cytosolTAScellular_component
GO:0006499N-terminal protein myristoylationIEAbiological_process
GO:0006915apoptotic processTASbiological_process
GO:0003824catalytic activityTASmolecular_function
GO:0030054cell junctionIDAcellular_component


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