| UniProt/SwissProt ID: | NINL_HUMAN |
| Description: | ninein-like [Source:HGNC Symbol;Acc:29163] |
| Location: | chr20 p11.21 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S686 | ELHEKsQEVIW | PhosphoSitePlus | |
| S185 | SEDFGsPQKSC | PhosphoSitePlus | |
| S87 | PSDEDsSSLES | PhosphoSitePlus | |
| S448 | YRERLsLLRSE | PhosphoSitePlus | |
| S87 | PSDEDsSSLES | PLK1 | phosphoELM |
| S589 | HSPSWsPDGRR | PhosphoSitePlus | |
| S1373 | LNKLVsRIAPA | PhosphoSitePlus | |
| S585 | PKNRHsPSWSP | PhosphoSitePlus | |
| S88 | SDEDSsSLESA | PhosphoSitePlus | |
| S88 | SDEDSsSLESA | PLK1 | phosphoELM |
| S686 | ELHEKsQEVIW | PLK1 | HPRD; phosphoELM |
| T161 | EEAEStKEAQN | PLK1 | HPRD; phosphoELM |
| T161 | EEAEStKEAQN | PhosphoSitePlus | |
| T758 | ARRDLtLELEE | PhosphoSitePlus | |
| Dephosphorylation site |
| NINL_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000278886 | G814R | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000278886 | G1045A | COSMIC | Pancreatic Cancer | 21252315 | ENSP00000278886 | D84N | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| NINL_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NINL_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PLK1_HUMAN | NINL_HUMAN | kinase -> substrate | RegPhos; Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| NINL_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005874 | microtubule | IEA | cellular_component |
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0005509 | calcium ion binding | IEA | molecular_function |
| GO:0000278 | mitotic cell cycle | TAS | biological_process |
| GO:0005815 | microtubule organizing center | IEA | cellular_component |
| GO:0005829 | cytosol | TAS | cellular_component |