| UniProt/SwissProt ID: | NIM1_HUMAN |
| Description: | Serine/threonine-protein kinase NIM1 [Source:UniProtKB/Swiss-Prot;Acc:Q8IY84] |
| Location: | chr5 p12 |
| Node attribute: | kinase |
| Phosphorylation site |
| NIM1_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| NIM1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000313572 | P333S | Greenman2007, HPI | Lung Cancer | 17344846 | ENSP00000313572 | R372* | Greenman2007 | Intestines Cancer | 17344846 | ENSP00000313572 | P411T | HPI | Non-small cell lung carcinoma | 17344846 | ENSP00000313572 | P411T | Greenman2007 | Lung Cancer | 17344846 | ENSP00000313572 | R372* | Greenman2007 | Breast Cancer | 17344846 |
| Differential expressed protein |
| NIM1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NIM1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| NIM1_HUMAN | CRK_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| NIM1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0000287 | magnesium ion binding | IDA | molecular_function |
| GO:0006468 | protein phosphorylation | IDA | biological_process |
| GO:0004674 | protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IDA | molecular_function |