UniProt/SwissProt ID: | NF1_HUMAN |
Description: | neurofibromin 1 [Source:HGNC Symbol;Acc:7765] |
Location: | chr17 q11.2 |
Node attribute: | PPI(source) |
Phosphorylation site |
Position | PhosphoPeptide | Catalytic kinase | Source |
---|---|---|---|
Y1521 | EKIGQyLSSNR | PhosphoSitePlus | |
Y2476 | VPMDTyPIHHG | PhosphoSitePlus; HPRD; phosphoELM | |
S2188 | RDRSFsPGSYE | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
S879 | KGSMIsVMSSE | PhosphoSitePlus | |
T2444 | LAALLtVSEEV | PhosphoSitePlus | |
Y863 | SGLATySPPMG | PhosphoSitePlus | |
S2543 | LGTRKsFDHLI | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
S2798 | RHGSAsQVQKQ | HPRD | |
S2819 | RHGSAsQVQKQ | PhosphoSitePlus; HPRD | |
S2502 | ARKSMsLDMGQ | HPRD | |
S2808 | QRSAGsFKRNS | HPRD | |
Y2503 | KGSEGyLAATY | PhosphoSitePlus | |
S56 | FSLVIsGLTTI | HPRD | |
Y2455 | VPMDTyPIHHG | HPRD | |
S2576 | HLRKVsVSESN | HPRD | |
S2802 | ENVELsPTTGH | HPRD | |
Y2577 | VAETDyEMETQ | PhosphoSitePlus; HPRD | |
S2515 | TVGQTsPRARK | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
S876 | SERKGsMISVM | PhosphoSitePlus | |
S2523 | ARKSMsLDMGQ | PhosphoSitePlus; HPRD; phosphoELM | |
S2460 | LKHRKsLLLTD | PhosphoSitePlus | |
T2507 | GYLAAtYPTVG | HPRD | |
S2496 | TQPWSsPKGSE | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
S864 | GLATYsPPMGP | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
S2474 | ETQPWsSPKGS | HPRD | |
Y2508 | YLAATyPTVGQ | PhosphoSitePlus; HPRD | |
T1435 | NHVLFtKEEHM | HPRD | |
S2500 | PRARKsMSLDM | HPRD | |
T1751 | LAHKDtKVSIK | PhosphoSitePlus | |
T2486 | GYLAAtYPTVG | HPRD | |
T915 | GLQIRtNVKDL | PhosphoSitePlus | |
S2495 | ETQPWsSPKGS | HPRD; phosphoELM | |
T60 | ISGLTtILKNV | HPRD | |
S2597 | HLRKVsVSESN | PhosphoSitePlus; HPRD | |
S2817 | RTRHGsASQVQ | PhosphoSitePlus; HPRD | |
S2522 | LGTRKsFDHLI | HPRD | |
S2167 | RDRSFsPGSYE | HPRD | |
T2493 | PTVGQtSPRAR | HPRD | |
S2834 | SFKRNsIKKIV | PhosphoSitePlus | |
S2561 | RQEMEsGITTP | PhosphoSitePlus | |
T1456 | NHVLFtKEEHM | HPRD | |
Y930 | LSPALyPMLFN | PhosphoSitePlus | |
Y2487 | YLAATyPTVGQ | HPRD | |
S2494 | TVGQTsPRARK | HPRD | |
T2565 | ESGITtPPKMR | PhosphoSitePlus | |
T676 | AGCSGtPPICR | PhosphoSitePlus | |
Y2556 | VAETDyEMETQ | HPRD | |
T2581 | DYEMEtQRISS | PhosphoSitePlus | |
S2446 | ALLTVsEEVRS | PhosphoSitePlus | |
T2489 | AATYPtVGQTS | HPRD | |
S465 | IRMAPsLTFKE | PhosphoSitePlus | |
S2521 | PRARKsMSLDM | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
S2599 | RKVSVsESNVL | PhosphoSitePlus | |
S2475 | TQPWSsPKGSE | HPRD | |
T2510 | AATYPtVGQTS | HPRD | |
S1567 | LNLTSsKFEEF | PhosphoSitePlus | |
T2514 | PTVGQtSPRAR | PhosphoSitePlus; HPRD; phosphoELM | |
S926 | VGLELsPALYP | PhosphoSitePlus | |
S2451 | SEEVRsRCSLK | PhosphoSitePlus | |
T467 | MAPSLtFKEKV | PhosphoSitePlus | |
S2829 | QRSAGsFKRNS | PhosphoSitePlus; phosphoELM | |
T59 | VISGLtTILKN | HPRD | |
S2781 | ENVELsPTTGH | HPRD | |
S882 | MISVMsSEGNA | PhosphoSitePlus | |
S674 | SAAGCsGTPPI | PhosphoSitePlus | |
S2796 | RTRHGsASQVQ | HPRD | |
S1140 | RLASLR | SysPTM 2.0 | |
Dephosphorylation site |
NF1_HUMAN do not have dephosphorylation site. |
Mutation site |
Ensembl ID | Variation | Source | Cancer name | Pubmed |
---|---|---|---|---|
ENSP00000351015 | V1757D | COSMIC | Other Cancer | 19142971 |
ENSP00000348498 | H809Y | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000348498 | G2724R | Sjoblom2006, BIOMART | Breast Cancer | 16959974, 21930507, 21930502 |
ENSP00000348498 | V1182F | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000351015 | R652C | COSMIC | Head and Neck Cancer | 21798893 |
ENSP00000351015 | R1306* | COSMIC | Neoplasms by Histologic Type | 14635100 |
ENSP00000351015 | P1951fs*6 | COSMIC | Other Cancer | 17960768 |
ENSP00000351015 | R1534* | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | Q1341* | COSMIC | Neoplasms by Histologic Type | 10677298 |
ENSP00000351015 | R461* | COSMIC | Neoplasms by Histologic Type | |
ENSP00000351015 | S2549* | COSMIC | Central Nervous System Neoplasms | |
ENSP00000351015 | D176E | COSMIC | Intestines Cancer | 12522551 |
ENSP00000351015 | A2336T | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | G849* | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000348498 | L210* | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
ENSP00000351015 | A1819T | COSMIC | Lung Cancer | 20668451 |
ENSP00000351015 | H712R | COSMIC | Intestines Cancer | 12522551 |
ENSP00000348498 | L550S | TCGA | Ovarian Cancer | 21720365, 18772890 |
ENSP00000351015 | R1412S | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | Q1447K | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | R416* | COSMIC | Neoplasms by Histologic Type | 18484666 |
ENSP00000351015 | R816* | COSMIC | Lung Cancer | 20668451 |
ENSP00000351015 | F1110fs*2 | COSMIC | Neoplasms by Histologic Type | 16941471 |
ENSP00000351015 | W696* | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000351015 | Q519P | COSMIC | Neoplasms by Histologic Type | 14722917 |
ENSP00000351015 | R681* | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000348498 | E163* | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000348498 | G849* | TCGA | Neoplasms by Histologic Type | 21720365, 18772890 |
ENSP00000351015 | T1598fs*26 | COSMIC | Neoplasms by Histologic Type | 16941471 |
ENSP00000351015 | Q1841* | COSMIC | Central Nervous System Neoplasms | 18772396 |
ENSP00000351015 | Q1987* | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000348498 | N2658D | BIOMART | Pancreatic Cancer | 21930507, 21930502 |
ENSP00000348498 | L1187I | BIOMART | Colorectal Cancer | 21930507, 21930502 |
ENSP00000348498 | S574T | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000351015 | Q756* | COSMIC | Neoplasms by Histologic Type | 11115850 |
ENSP00000351015 | K1444E | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000351015 | R1276* | COSMIC | Lymphoma | 20067559 |
ENSP00000351015 | H553R | COSMIC | Neoplasms by Histologic Type | 20655465 |
ENSP00000351015 | S2597* | COSMIC | Neoplasms by Histologic Type | 19738042 |
ENSP00000348498 | E1198* | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000351015 | G2745R | HPI, COSMIC | Breast Cancer | 7981724 8825042 16959974 |
ENSP00000351015 | Q2589* | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000351015 | L21R | COSMIC | Other Cancer | 19142971 |
ENSP00000351015 | S402L | COSMIC | Breast Cancer | 20668451 |
ENSP00000351015 | L2158* | COSMIC | Lymphoma | 20505189 |
ENSP00000351015 | D633fs*55 | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | K2171* | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000351015 | R1241* | COSMIC | Neoplasms by Histologic Type | 10677298 |
ENSP00000351015 | D1302Y | COSMIC | Intestines Cancer | 18592002 |
ENSP00000351015 | S2484F | COSMIC | Melanoma | |
ENSP00000351015 | N1984T | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000351015 | Q554E | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000348498 | R997K | TCGA | Neoplasms by Histologic Type | 21720365, 18772890 |
ENSP00000348498 | Q1820* | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
ENSP00000351015 | W1258* | COSMIC | Neoplasms by Histologic Type | 16941471 |
ENSP00000351015 | N2679D | BIOMART | Pancreatic Cancer | 21930507, 21930502 |
ENSP00000351015 | Q684* | COSMIC | Neoplasms by Histologic Type | 16941471 |
ENSP00000351015 | Q535* | COSMIC | Lymphoma | |
ENSP00000351015 | E1720* | COSMIC | Gastric Cancer | |
ENSP00000348498 | Q112* | TCGA | Ovarian Cancer | 21720365, 18772890 |
ENSP00000351015 | Q209H | COSMIC | Central Nervous System Neoplasms | |
ENSP00000351015 | L1590* | COSMIC | Neoplasms by Histologic Type | 18484666 |
ENSP00000351015 | A2032T | COSMIC | Pancreatic Cancer | 21252315 |
ENSP00000351015 | I878T | COSMIC | Lung Cancer | 20668451 |
ENSP00000351015 | E163* | COSMIC | Lung Cancer | 18948947 |
ENSP00000348498 | R2237* | BIOMART | Brain Cancer | 21930507, 21930502 |
ENSP00000351015 | R1968* | COSMIC | Central Nervous System Neoplasms | 18772396 |
ENSP00000351015 | P678fs*10 | COSMIC | Intestines Cancer | 12522551 |
ENSP00000351015 | V1182F | COSMIC | Lung Cancer | 18948947 |
ENSP00000348498 | P1930L | Sjoblom2006 | Intestines Cancer | 16959974, 21930507, 21930502 |
ENSP00000351015 | I1223V | COSMIC | Lung Cancer | 20668451 |
ENSP00000351015 | L1587* | COSMIC | Neoplasms by Histologic Type | 16941471 |
ENSP00000351015 | P1548L | COSMIC | Lung Cancer | 20668451 |
ENSP00000351015 | M799fs*22 | COSMIC | Lung Cancer | |
ENSP00000351015 | L1187I | HPI | Colorectal Cancer | 7981724 8825042 16959974 |
ENSP00000351015 | F250fs*31 | COSMIC | Neoplasms by Histologic Type | 17551851 |
ENSP00000351015 | Q1336* | COSMIC | Melanoma | |
ENSP00000351015 | L2416V | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000351015 | R1830C | COSMIC | Central Nervous System Neoplasms | 18772396 |
ENSP00000351015 | R997K | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | T2004fs*8 | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | R1362* | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000348498 | P1930L | BIOMART | Colorectal Cancer | 21930507, 21930502 |
ENSP00000351015 | E91K | COSMIC | Neoplasms by Histologic Type | 18484666 |
ENSP00000351015 | L1946fs*4 | COSMIC | Neoplasms by Histologic Type | 11409870 |
ENSP00000348498 | L194P | TCGA | Ovarian Cancer | 21720365, 18772890 |
ENSP00000351015 | R304* | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | P1951L | COSMIC | Intestines Cancer | 16959974 |
ENSP00000348498 | S1140* | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
ENSP00000351015 | Q369* | COSMIC | Neoplasms by Histologic Type | 16941471 |
ENSP00000351015 | N939fs*15 | COSMIC | Neoplasms by Histologic Type | 11409870 |
ENSP00000351015 | L532fs*24 | COSMIC | Other Cancer | 17960768 |
ENSP00000351015 | D2375H | BIOMART | Breast Cancer | 21930507, 21930502 |
ENSP00000351015 | L194P | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000351015 | N1603fs*21 | COSMIC | Neoplasms by Histologic Type | 17551851 |
ENSP00000351015 | S1150L | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000351015 | S1100A | COSMIC | Ovarian Cancer | 20668451 |
ENSP00000351015 | S2181G | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000351015 | G949fs*5 | COSMIC | Neoplasms by Histologic Type | 17551851 |
ENSP00000351015 | E2501fs*22 | COSMIC | Neoplasms by Histologic Type | 16941471 |
ENSP00000348498 | R192* | TCGA | Neoplasms by Histologic Type | 21720365, 18772890 |
ENSP00000351015 | S2810G | COSMIC | Lung Cancer | 20668451 |
ENSP00000348498 | Q209H | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
ENSP00000351015 | H712R | HPI | Other Cancer | 7981724 8825042 12522551 |
ENSP00000351015 | R135fs*30 | COSMIC | Neoplasms by Histologic Type | 19738042 |
ENSP00000351015 | Q1017* | COSMIC | Neoplasms by Histologic Type | 14635100 |
ENSP00000351015 | R192* | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | R2150S | COSMIC | Neoplasms by Histologic Type | 14722917 |
ENSP00000351015 | W2317* | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | R1204W | COSMIC | Ovarian Cancer | 20668451 |
ENSP00000351015 | D2635fs*9 | COSMIC | Central Nervous System Neoplasms | |
ENSP00000351015 | K1771* | COSMIC | Neoplasms by Histologic Type | 22034633 |
ENSP00000351015 | W696fs*1 | COSMIC | Neoplasms by Histologic Type | 14722917 |
ENSP00000351015 | R440* | COSMIC | Neoplasms by Histologic Type | 22034633 |
ENSP00000351015 | E1919K | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | C167* | COSMIC | Thyroid Carcinoma | |
ENSP00000351015 | L180* | COSMIC | Other Cancer | 19142971 |
ENSP00000351015 | S749* | COSMIC | Neoplasms by Histologic Type | 11409870 |
ENSP00000351015 | G1649R | COSMIC | Head and Neck Cancer | 21798893 |
ENSP00000348498 | E517* | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000351015 | V2391F | COSMIC | Lung Cancer | 20668451 |
ENSP00000351015 | C1063* | COSMIC | Neoplasms by Histologic Type | 16941471 |
ENSP00000348498 | R304* | TCGA | Neoplasms by Histologic Type | 21720365, 18772890 |
ENSP00000351015 | G922V | COSMIC | Lung Cancer | 18948947 |
ENSP00000348498 | D2354H | BIOMART | Breast Cancer | 21930507, 21930502 |
ENSP00000351015 | L274R | COSMIC | Lymphoma | 20015894 |
ENSP00000351015 | C1882F | COSMIC | Lung Cancer | 18948947 |
ENSP00000351015 | P1951L | HPI | Colorectal Cancer | 7981724 8825042 16959974 |
ENSP00000351015 | Q2588* | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000351015 | I941fs*13 | COSMIC | Central Nervous System Neoplasms | |
ENSP00000351015 | Y2285* | COSMIC | Other Cancer | 19142971 |
ENSP00000348498 | K1423N | BIOMART | chronic lymphocytic leukemia | 21930507, 21930502 |
ENSP00000351015 | H809Y | COSMIC | Lung Cancer | 18948947 |
ENSP00000351015 | R1136W | COSMIC | Lung Cancer | 20668451 |
ENSP00000351015 | R1276Q | COSMIC | Intestines Cancer | 12522551 |
ENSP00000351015 | S1140* | COSMIC | Central Nervous System Neoplasms | |
ENSP00000348498 | L1187I | Sjoblom2006 | Intestines Cancer | 16959974, 7981724, 8825042, 21930507, 21930502 |
ENSP00000348498 | G922V | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000351015 | L2338fs*8 | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | E2214* | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000351015 | D2632E + p.E2633* | Ding2008 | Lung Cancer | 18948947 |
ENSP00000348498 | S2311* | TCGA | Neoplasms by Histologic Type | 21720365, 18772890 |
ENSP00000351015 | A74D | HPI | Other Cancer | 7981724 8825042 12522551 |
ENSP00000351015 | D176E | HPI | Other Cancer | 7981724 8825042 10712197 12522551 15146469 15060124 10726756 |
ENSP00000348498 | C1861F | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000348498 | R1809C | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
ENSP00000351015 | I23L | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000348498 | S2528* | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
ENSP00000351015 | S1759F | COSMIC | Skin Cancer | 21984974 |
ENSP00000351015 | W1662* | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | P2477S | COSMIC | Intestines Cancer | 12522551 |
ENSP00000351015 | S2332* | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000348498 | Q835H | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000351015 | S1786* | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000348498 | I526S | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
ENSP00000351015 | D1849N | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | E517* | COSMIC | Lung Cancer | 18948947 |
ENSP00000351015 | L210* | COSMIC | Central Nervous System Neoplasms | |
ENSP00000351015 | L161* | COSMIC | Lymphoma | 20015894 |
ENSP00000351015 | Y1106C | COSMIC | Hepatocellular Carcinoma | 21822264 |
ENSP00000351015 | R1769* | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | M1539I | COSMIC | Skin Cancer | 21984974 |
ENSP00000351015 | Q112* | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000351015 | L1187I | Sjoblom2006, COSMIC | Intestines Cancer | 16959974, 7981724, 8825042, 7981724, 8825042, 16959974 |
ENSP00000351015 | E1198* | COSMIC | Lung Cancer | 18948947 |
ENSP00000351015 | N2341fs*5 | COSMIC | Intestines Cancer | |
ENSP00000351015 | Q835H | COSMIC | Lung Cancer | 18948947 |
ENSP00000348498 | F1392V | BIOMART | Hepatocellular Carcinoma | 21930507, 21930502 |
ENSP00000351015 | K1099I | COSMIC | Central Nervous System Neoplasms | |
ENSP00000351015 | L550P | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000348498 | K1099I | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
ENSP00000351015 | R385fs*2 | COSMIC | Neoplasms by Histologic Type | 16941471 |
ENSP00000351015 | E1688* | COSMIC | Head and Neck Cancer | 21798893 |
ENSP00000351015 | A1858T | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000348498 | G1842A | TCGA | Ovarian Cancer | 21720365, 18772890 |
ENSP00000351015 | Q2302fs*17 | COSMIC | Central Nervous System Neoplasms | 18772890 |
ENSP00000351015 | Y1607fs*17 | COSMIC | Intestines Cancer | 12522551 |
ENSP00000351015 | D2095fs*16 | COSMIC | Other Cancer | 19142971 |
ENSP00000351015 | P2472H | COSMIC | Prostate Cancer | 12522551 |
ENSP00000351015 | G1863A | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000351015 | R2450* | COSMIC | Neoplasms by Histologic Type | 14722917 |
ENSP00000351015 | F2156L | COSMIC | Renal Cancer | 20054297 |
ENSP00000351015 | Y628fs*3 | COSMIC | Intestines Cancer | |
ENSP00000351015 | V630fs*1 | COSMIC | Neoplasms by Histologic Type | 14722917 |
ENSP00000351015 | I526S | COSMIC | Central Nervous System Neoplasms | |
ENSP00000351015 | E196* | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000351015 | Q1815* | COSMIC | Neoplasms by Histologic Type | 20358387 |
ENSP00000351015 | K583R | COSMIC | Lymphoma | 20015894 |
ENSP00000351015 | A74D | COSMIC | Intestines Cancer | 12522551 |
ENSP00000348498 | R1947* | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
ENSP00000351015 | S574T | COSMIC | Lung Cancer | 18948947 |
Differential expressed protein |
NF1_HUMAN is not differential expressed protein. |
Hyperphosphorylation site |
NF1_HUMAN do not have hyperphosphorylation site. |
Direct Interaction Pair |
Source | Target | Relationship | Resource |
---|---|---|---|
NF1_HUMAN | RRAS2_HUMAN | other | KEGG |
Function Annotation |
KEGG Pathway |
KEGG ID | Pathway |
---|---|
hsa04010 | MAPK signaling pathway |
Gene Ontology |
GO ID | GO_Term | Evidence | Ontology |
---|---|---|---|
GO:0014044 | Schwann cell development | ISS | biological_process |
GO:0048169 | regulation of long-term neuronal synaptic plastici | IEA | biological_process |
GO:0030336 | negative regulation of cell migration | IMP | biological_process |
GO:0045765 | regulation of angiogenesis | IMP | biological_process |
GO:0000165 | MAPK cascade | IEA | biological_process |
GO:0001649 | osteoblast differentiation | IEA | biological_process |
GO:0005488 | binding | IEA | molecular_function |
GO:0048485 | sympathetic nervous system development | IEA | biological_process |
GO:0042127 | regulation of cell proliferation | IEA | biological_process |
GO:0030336 | negative regulation of cell migration | IEA | biological_process |
GO:0007154 | cell communication | ISS | biological_process |
GO:0021915 | neural tube development | IEA | biological_process |
GO:0005737 | cytoplasm | IEA | cellular_component |
GO:0032320 | positive regulation of Ras GTPase activity | ISS | biological_process |
GO:0008542 | visual learning | IEA | biological_process |
GO:0046580 | negative regulation of Ras protein signal transduc | IBA | biological_process |
GO:0048485 | sympathetic nervous system development | ISS | biological_process |
GO:0022011 | myelination in peripheral nervous system | ISS | biological_process |
GO:0035021 | negative regulation of Rac protein signal transduc | IEA | biological_process |
GO:0001952 | regulation of cell-matrix adhesion | ISS | biological_process |
GO:0030325 | adrenal gland development | ISS | biological_process |
GO:0001666 | response to hypoxia | ISS | biological_process |
GO:0022011 | myelination in peripheral nervous system | IEA | biological_process |
GO:0030424 | axon | IDA | cellular_component |
GO:0006469 | negative regulation of protein kinase activity | IEA | biological_process |
GO:0007422 | peripheral nervous system development | IEA | biological_process |
GO:0043065 | positive regulation of apoptotic process | ISS | biological_process |
GO:0042992 | negative regulation of transcription factor import | IEA | biological_process |
GO:0006469 | negative regulation of protein kinase activity | ISS | biological_process |
GO:0021897 | forebrain astrocyte development | IEA | biological_process |
GO:0043525 | positive regulation of neuron apoptotic process | IEA | biological_process |
GO:0021510 | spinal cord development | IEA | biological_process |
GO:0007519 | skeletal muscle tissue development | IEA | biological_process |
GO:0045685 | regulation of glial cell differentiation | ISS | biological_process |
GO:0043409 | negative regulation of MAPK cascade | ISS | biological_process |
GO:0001889 | liver development | IEA | biological_process |
GO:0048853 | forebrain morphogenesis | IEA | biological_process |
GO:0043525 | positive regulation of neuron apoptotic process | ISS | biological_process |
GO:0030036 | actin cytoskeleton organization | ISS | biological_process |
GO:0005622 | intracellular | IEA | cellular_component |
GO:0030036 | actin cytoskeleton organization | IEA | biological_process |
GO:0045124 | regulation of bone resorption | IEA | biological_process |
GO:0014065 | phosphatidylinositol 3-kinase cascade | IEA | biological_process |
GO:0043473 | pigmentation | ISS | biological_process |
GO:0007406 | negative regulation of neuroblast proliferation | ISS | biological_process |
GO:0014044 | Schwann cell development | IEA | biological_process |
GO:0030425 | dendrite | IDA | cellular_component |
GO:0021987 | cerebral cortex development | IEA | biological_process |
GO:0030198 | extracellular matrix organization | ISS | biological_process |
GO:0042060 | wound healing | IEA | biological_process |
GO:0043407 | negative regulation of MAP kinase activity | ISS | biological_process |
GO:0007422 | peripheral nervous system development | ISS | biological_process |
GO:0048853 | forebrain morphogenesis | ISS | biological_process |
GO:0030325 | adrenal gland development | IEA | biological_process |
GO:0043535 | regulation of blood vessel endothelial cell migrat | IMP | biological_process |
GO:0001889 | liver development | ISS | biological_process |
GO:0014065 | phosphatidylinositol 3-kinase cascade | ISS | biological_process |
GO:0007265 | Ras protein signal transduction | ISS | biological_process |
GO:0043409 | negative regulation of MAPK cascade | IEA | biological_process |
GO:0032228 | regulation of synaptic transmission, GABAergic | IEA | biological_process |
GO:0001953 | negative regulation of cell-matrix adhesion | IEA | biological_process |
GO:0005634 | nucleus | ISS | cellular_component |
GO:0001656 | metanephros development | ISS | biological_process |
GO:0046929 | negative regulation of neurotransmitter secretion | IEA | biological_process |
GO:0050890 | cognition | IMP | biological_process |
GO:0001938 | positive regulation of endothelial cell proliferat | IEA | biological_process |
GO:0007165 | signal transduction | IEA | biological_process |
GO:0008542 | visual learning | ISS | biological_process |
GO:0001656 | metanephros development | IEA | biological_process |
GO:0048715 | negative regulation of oligodendrocyte differentia | ISS | biological_process |
GO:0001937 | negative regulation of endothelial cell proliferat | IMP | biological_process |
GO:0021510 | spinal cord development | ISS | biological_process |
GO:0005515 | protein binding | IEA | molecular_function |
GO:0030199 | collagen fibril organization | IEA | biological_process |
GO:0005515 | protein binding | IPI | molecular_function |
GO:0007154 | cell communication | IEA | biological_process |
GO:0048715 | negative regulation of oligodendrocyte differentia | IEA | biological_process |
GO:0048745 | smooth muscle tissue development | ISS | biological_process |
GO:0051056 | regulation of small GTPase mediated signal transdu | IEA | biological_process |
GO:0045762 | positive regulation of adenylate cyclase activity | IEA | biological_process |
GO:0046580 | negative regulation of Ras protein signal transduc | IEA | biological_process |
GO:0048593 | camera-type eye morphogenesis | ISS | biological_process |
GO:0001666 | response to hypoxia | IEA | biological_process |
GO:0000165 | MAPK cascade | ISS | biological_process |
GO:0032318 | regulation of Ras GTPase activity | IMP | biological_process |
GO:0007507 | heart development | IEA | biological_process |
GO:0016525 | negative regulation of angiogenesis | IEA | biological_process |
GO:0001952 | regulation of cell-matrix adhesion | IEA | biological_process |
GO:0043473 | pigmentation | IEA | biological_process |
GO:0045671 | negative regulation of osteoclast differentiation | IEA | biological_process |
GO:0001649 | osteoblast differentiation | ISS | biological_process |
GO:0007420 | brain development | ISS | biological_process |
GO:0048844 | artery morphogenesis | ISS | biological_process |
GO:0043065 | positive regulation of apoptotic process | IEA | biological_process |
GO:0005737 | cytoplasm | IBA | cellular_component |
GO:0005099 | Ras GTPase activator activity | IDA | molecular_function |
GO:0048844 | artery morphogenesis | IEA | biological_process |
GO:0048712 | negative regulation of astrocyte differentiation | IEA | biological_process |
GO:0048745 | smooth muscle tissue development | IEA | biological_process |
GO:0008285 | negative regulation of cell proliferation | IEA | biological_process |
GO:0045762 | positive regulation of adenylate cyclase activity | ISS | biological_process |
GO:0007420 | brain development | IEA | biological_process |
GO:0048593 | camera-type eye morphogenesis | IEA | biological_process |
GO:0030198 | extracellular matrix organization | IEA | biological_process |
GO:0005096 | GTPase activator activity | IEA | molecular_function |
GO:0048147 | negative regulation of fibroblast proliferation | IEA | biological_process |
GO:0045124 | regulation of bone resorption | ISS | biological_process |
GO:0007265 | Ras protein signal transduction | IEA | biological_process |
GO:0030199 | collagen fibril organization | ISS | biological_process |
GO:0032320 | positive regulation of Ras GTPase activity | IEA | biological_process |
GO:0007406 | negative regulation of neuroblast proliferation | IEA | biological_process |
GO:0021897 | forebrain astrocyte development | ISS | biological_process |
GO:0042992 | negative regulation of transcription factor import | ISS | biological_process |
GO:0031235 | intrinsic to internal side of plasma membrane | IBA | cellular_component |
GO:0007507 | heart development | ISS | biological_process |
GO:0045765 | regulation of angiogenesis | IEA | biological_process |
GO:0001937 | negative regulation of endothelial cell proliferat | IEA | biological_process |
GO:0045685 | regulation of glial cell differentiation | IEA | biological_process |
GO:0021987 | cerebral cortex development | ISS | biological_process |
GO:0043407 | negative regulation of MAP kinase activity | IEA | biological_process |
GO:0042060 | wound healing | ISS | biological_process |