| UniProt/SwissProt ID: | NEUM_HUMAN |
| Description: | growth associated protein 43 [Source:HGNC Symbol;Acc:4140] |
| Location: | chr3 q13.31 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S202 | TETGEsSQAEE | CSNK2A1 | HPRD |
| S96 | APATGsKPDEP | HPRD; RegPhos | |
| T36 | AHKAAtKIQAS | IQ | PhosphoSitePlus |
| S202 | TETGEsSQAEE | CK2_group | RegPhos |
| T94 | EAAPAtGSKPD | RegPhos | |
| S131 | QAPASsEEKAG | Neuromodulin | PhosphoSitePlus |
| S41 | TKIQAsFRGHI | PKCb | RegPhos |
| S41 | TKIQAsFRGHI | IQ | PhosphoSitePlus |
| S142 | SAETEsATKAS | HPRD | |
| S147 | SATKAsTDNSP | Neuromodulin | PhosphoSitePlus |
| T181 | AAAATtPAAED | RegPhos | |
| T107 | GKAGEtPSEEK | HPRD | |
| S109 | AGETPsEEKKG | HPRD | |
| S142 | SAETEsATKAS | Neuromodulin | PhosphoSitePlus |
| S109 | AGETPsEEKKG | Neuromodulin | PhosphoSitePlus |
| S203 | ETGESsQAEEN | CK2_group | RegPhos |
| T107 | GKAGEtPSEEK | Neuromodulin | PhosphoSitePlus |
| T144 | ETESAtKASTD | Neuromodulin | PhosphoSitePlus |
| T148 | ATKAStDNSPS | Neuromodulin | PhosphoSitePlus |
| S151 | ASTDNsPSSKA | Neuromodulin | PhosphoSitePlus |
| S203 | ETGESsQAEEN | CSNK2A1 | HPRD |
| S203 | ETGESsQAEEN | CK2a1 | RegPhos |
| S202 | TETGEsSQAEE | CK2a1-rs | RegPhos |
| S154 | DNSPSsKAEDA | Neuromodulin | PhosphoSitePlus |
| S202 | TETGEsSQAEE | CK2a1 | RegPhos |
| S41 | TKIQAsFRGHI | PRKCB | HPRD |
| S203 | ETGESsQAEEN | CK2a1-rs | RegPhos |
| S154 | DNSPSsKAEDA | HPRD | |
| T181 | AAAATtPAAED | Neuromodulin | PhosphoSitePlus |
| S41 | TKIQAsFRGHI | RegPhos | |
| Dephosphorylation site |
| NEUM_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000305010 | D29E | COSMIC | Skin Cancer | 21984974 | ENSP00000305010 | E79Q | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000305010 | T215I | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000305010 | Testicular Cancer | Normal vs. Cancer | cell line | Up | 18489135 | |
| Hyperphosphorylation site |
| NEUM_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | NEUM_HUMAN | kinase -> substrate | RegPhos |
| KPCB_HUMAN | NEUM_HUMAN | kinase -> substrate | HPRD |
| CSK21_HUMAN | NEUM_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| NEUM_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0010001 | glial cell differentiation | IEA | biological_process |
| GO:0007411 | axon guidance | IEA | biological_process |
| GO:0030054 | cell junction | IEA | cellular_component |
| GO:0071944 | cell periphery | IEA | cellular_component |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0045202 | synapse | IEA | cellular_component |
| GO:0030424 | axon | IEA | cellular_component |
| GO:0040008 | regulation of growth | IEA | biological_process |
| GO:0042246 | tissue regeneration | IEA | biological_process |
| GO:0005516 | calmodulin binding | IEA | molecular_function |
| GO:0007205 | protein kinase C-activating G-protein coupled rece | TAS | biological_process |
| GO:0009611 | response to wounding | TAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0045165 | cell fate commitment | IEA | biological_process |
| GO:0007399 | nervous system development | IEA | biological_process |
| GO:0031527 | filopodium membrane | IDA | cellular_component |
| GO:0032584 | growth cone membrane | IEA | cellular_component |
| GO:0051489 | regulation of filopodium assembly | IDA | biological_process |
| GO:0016198 | axon choice point recognition | IEA | biological_process |