Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MSHR_HUMAN
Description:melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) [Source:HGNC Symbol;Acc:6929]
Location:chr16 q24.3
Node attribute:GPCR; receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T157YHSIVtLPRAR7tm_1PhosphoSitePlus
T308QELRRtLKEVLPhosphoSitePlus
S316EVLTCsW____PhosphoSitePlus
S154ALRYHsIVTLP7tm_1PhosphoSitePlus

Dephosphorylation site
MSHR_HUMAN do not have dephosphorylation site.

Mutation site
MSHR_HUMAN do not have mutation site.

Differential expressed protein
MSHR_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MSHR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
COLI_HUMANMSHR_HUMANligand -> receptorHPMR
ASIP_HUMANMSHR_HUMANligand -> receptorHPMR
MSHR_HUMANGNAS1_HUMANGPCR -> GproteingpDB
MSHR_HUMANGNAS2_HUMANGPCR -> GproteingpDB
IP3KA_HUMANMSHR_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04916Melanogenesis
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0090037positive regulation of protein kinase C signaling ISSbiological_process
GO:0043473pigmentationIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0070914UV-damage excision repairIDAbiological_process
GO:0004980melanocyte-stimulating hormone receptor activityIEAmolecular_function
GO:0009650UV protectionTASbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0004977melanocortin receptor activityTASmolecular_function
GO:0031625ubiquitin protein ligase bindingIPImolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0004977melanocortin receptor activityIEAmolecular_function
GO:0045944positive regulation of transcription from RNA polyISSbiological_process
GO:0051897positive regulation of protein kinase B signaling IEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0007187G-protein coupled receptor signaling pathway, coupTASbiological_process
GO:0007243intracellular protein kinase cascadeISSbiological_process
GO:0051897positive regulation of protein kinase B signaling ISSbiological_process
GO:0043473pigmentationTASbiological_process
GO:0008528G-protein coupled peptide receptor activityTASmolecular_function
GO:0007275multicellular organismal developmentTASbiological_process
GO:0030819positive regulation of cAMP biosynthetic processIDAbiological_process
GO:0019233sensory perception of painIEAbiological_process
GO:0010739positive regulation of protein kinase A signaling ISSbiological_process
GO:0004980melanocyte-stimulating hormone receptor activityIPImolecular_function
GO:0090037positive regulation of protein kinase C signaling IEAbiological_process
GO:0032720negative regulation of tumor necrosis factor produIMPbiological_process
GO:0015630microtubule cytoskeletonIDAcellular_component
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0042438melanin biosynthetic processIEAbiological_process
GO:0007243intracellular protein kinase cascadeIEAbiological_process
GO:0010739positive regulation of protein kinase A signaling IEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process