| UniProt/SwissProt ID: | MRVI1_HUMAN |
| Description: | murine retrovirus integration site 1 homolog [Source:HGNC Symbol;Acc:7237] |
| Location: | chr11 p15.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S657 | TARSMsLTLGK | RegPhos | |
| S670 | PRRRVsVAVVP | RegPhos | |
| S480 | LPSELsPAIEE | HPRD | |
| S707 | PNGKGsLPVTS | MRVI1 | PhosphoSitePlus |
| S199 | PTSSRsNSLTV | PhosphoSitePlus | |
| S110 | PHKRLsHRHLK | RegPhos | |
| S696 | SIPSLpALSES | PKG1 | RegPhos |
| S670 | PRRRVsVAVVP | MRVI1 | PhosphoSitePlus |
| S367 | LLRGLsWDSGP | MRVI1 | PhosphoSitePlus |
| S462 | LPSELsPAIEE | MRVI1 | PhosphoSitePlus |
| S320 | SPLPRsPTQDA | MRVI1 | PhosphoSitePlus |
| S689 | GQTPSsSSIPS | PKG1/cGK-I | phosphoELM |
| S367 | LLRGLsWDSGP | RegPhos | |
| S197 | ASPTSsRSNSL | PhosphoSitePlus | |
| S385 | LLRGLsWDSGP | HPRD | |
| S162 | EAKLVsERFLT | HPRD | |
| S191 | PNLSPsASPTS | PhosphoSitePlus | |
| Dephosphorylation site |
| MRVI1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000412229 | M44I | COSMIC | Central Nervous System Neoplasms | ENSP00000412229 | R486C | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| MRVI1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| MRVI1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | MRVI1_HUMAN | kinase -> substrate | RegPhos |
| KGP1_HUMAN | MRVI1_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04270 | Vascular smooth muscle contraction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0005789 | endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0007596 | blood coagulation | TAS | biological_process |
| GO:0031095 | platelet dense tubular network membrane | TAS | cellular_component |
| GO:0016529 | sarcoplasmic reticulum | IEA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0048471 | perinuclear region of cytoplasm | IEA | cellular_component |