Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MLRV_HUMAN
Description:myosin, light chain 2, regulatory, cardiac, slow [Source:HGNC Symbol;Acc:7583]
Location:chr12 q24.11
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y152TGNLDyKNLVHefhandPhosphoSitePlus
Y118VLKADyVREMLefhandPhosphoSitePlus
S15AGGANsNVFSMPhosphoSitePlus
T124VREMLtTQAERefhandPhosphoSitePlus
S19NSNVFsMFEQTPhosphoSitePlus
S19NSNVFsMFEQTCDC42BPAHPRD

Dephosphorylation site
MLRV_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000228841D48YCOSMICOvarian Cancer21720365

Differential expressed protein
MLRV_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MLRV_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MRCKA_HUMANMLRV_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa04260Cardiac muscle contraction
hsa04510Focal adhesion
hsa04810Regulation of actin cytoskeleton
hsa04530Tight junction
hsa05414Dilated cardiomyopathy
hsa04670Leukocyte transendothelial migration

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0055010ventricular cardiac muscle tissue morphogenesisIMPbiological_process
GO:0060048cardiac muscle contractionIEAbiological_process
GO:0032036myosin heavy chain bindingNASmolecular_function
GO:0030017sarcomereTAScellular_component
GO:0060047heart contractionIEAbiological_process
GO:0008307structural constituent of muscleNASmolecular_function
GO:0015629actin cytoskeletonIDAcellular_component
GO:0060047heart contractionISSbiological_process
GO:0030049muscle filament slidingTASbiological_process
GO:0016459myosin complexTAScellular_component
GO:0009791post-embryonic developmentIEAbiological_process
GO:0030016myofibrilIEAcellular_component
GO:0003007heart morphogenesisIEAbiological_process
GO:0007507heart developmentIEAbiological_process
GO:0030308negative regulation of cell growthIMPbiological_process
GO:0055003cardiac myofibril assemblyIEAbiological_process
GO:0005829cytosolTAScellular_component
GO:0006942regulation of striated muscle contractionTASbiological_process
GO:0005509calcium ion bindingIEAmolecular_function
GO:0042694muscle cell fate specificationIEAbiological_process
GO:0048747muscle fiber developmentIEAbiological_process
GO:0005856cytoskeletonIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0003785actin monomer bindingIDAmolecular_function


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