| UniProt/SwissProt ID: | MFNG_HUMAN |
| Description: | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:7038] |
| Location: | chr22 q13.1 |
| Node attribute: | glycosylation(source) |
| Phosphorylation site |
| MFNG_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| MFNG_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000349490 | K122M | COSMIC | Lung Cancer | 20668451 |
| Differential expressed protein |
| MFNG_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| MFNG_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MFNG_HUMAN | NOTC2_HUMAN | glycosylation | NetPath |
| MFNG_HUMAN | DLL1_HUMAN | glycosylation | NetPath |
| MFNG_HUMAN | JAG1_HUMAN | glycosylation | NetPath |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa00514 | Other types of O-glycan biosynthesis |
| hsa04330 | Notch signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransf | IEA | molecular_function |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0045747 | positive regulation of Notch signaling pathway | IEA | biological_process |
| GO:0030173 | integral to Golgi membrane | IEA | cellular_component |
| GO:0016757 | transferase activity, transferring glycosyl groups | IEA | molecular_function |
| GO:0005615 | extracellular space | TAS | cellular_component |
| GO:0007389 | pattern specification process | IEA | biological_process |
| GO:0032092 | positive regulation of protein binding | IEA | biological_process |