Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MEP1B_HUMAN
Description:meprin A, beta [Source:HGNC Symbol;Acc:7020]
Location:chr18 q12.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T611DLCSKtTCKNDEGFPhosphoSitePlus
S687YRERMsSNRPNPKC_groupphosphoELM; RegPhos
S192NFNTYsDDISDAstacinPhosphoSitePlus
T620NDGVCtVRDGKEGFPhosphoSitePlus
S196YSDDIsDSLNVAstacinPhosphoSitePlus
S242QRMDFsDSDLLAstacinPhosphoSitePlus
S687YRERMsSNRPNPKCdRegPhos
S687YRERMsSNRPNPhosphoSitePlus
T612LCSKTtCKNDGEGFPhosphoSitePlus
S244MDFSDsDLLKLAstacinPhosphoSitePlus
S687YRERMsSNRPNPRKCDHPRD
S198DDISDsLNVPYAstacinPhosphoSitePlus

Dephosphorylation site
MEP1B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000269202T223ITCGAOvarian Cancer21720365, 18772890
ENSP00000269202S560TTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
MEP1B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MEP1B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCD_HUMANMEP1B_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04974Protein digestion and absorption

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008270zinc ion bindingIEAmolecular_function
GO:0007586digestionTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0005887integral to plasma membraneTAScellular_component
GO:0006954inflammatory responseIEAbiological_process
GO:0008237metallopeptidase activityIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0006508proteolysisIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0005615extracellular spaceTAScellular_component
GO:0004222metalloendopeptidase activityIEAmolecular_function


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