Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MD2L2_HUMAN
Description:MAD2 mitotic arrest deficient-like 2 (yeast) [Source:HGNC Symbol;Acc:6764]
Location:chr1 p36.22
Node attribute:PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T191LIPLKtMTSDIPhosphoSitePlus

Dephosphorylation site
MD2L2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000235310L123fs*6COSMICOvarian Cancer21720365
ENSP00000365882L123fs*6COSMICOvarian Cancer21720365
ENSP00000365855L123fs*6COSMICOvarian Cancer21720365

Differential expressed protein
MD2L2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MD2L2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MD1L1_HUMANMD2L2_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05131Shigellosis
hsa04110Cell cycle
hsa05100Bacterial invasion of epithelial cells
hsa04114Oocyte meiosis
hsa04914Progesterone-mediated oocyte maturation

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:2000678negative regulation of transcription regulatory reIMPbiological_process
GO:0090090negative regulation of canonical Wnt receptor signIMPbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0043433negative regulation of sequence-specific DNA bindiIDAbiological_process
GO:0008432JUN kinase bindingIDAmolecular_function
GO:0007015actin filament organizationIMPbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0001102RNA polymerase II activating transcription factor IPImolecular_function
GO:2000048negative regulation of cell-cell adhesion mediatedIMPbiological_process
GO:0010944negative regulation of transcription by competitivIMPbiological_process
GO:0001558regulation of cell growthIGIbiological_process
GO:0007067mitosisIEAbiological_process
GO:0005819spindleIDAcellular_component
GO:0060564negative regulation of mitotic anaphase-promoting IDAbiological_process
GO:0042177negative regulation of protein catabolic processIDAbiological_process
GO:0042772DNA damage response, signal transduction resultingIDAbiological_process
GO:0051301cell divisionIEAbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0006302double-strand break repairIGIbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0010719negative regulation of epithelial to mesenchymal tIMPbiological_process
GO:0000122negative regulation of transcription from RNA polyIDAbiological_process
GO:0016035zeta DNA polymerase complexIDAcellular_component
GO:0005680anaphase-promoting complexIDAcellular_component
GO:0006281DNA repairTASbiological_process
GO:0033138positive regulation of peptidyl-serine phosphorylaIDAbiological_process
GO:0007094mitotic cell cycle spindle assembly checkpointTASbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIMPbiological_process