| UniProt/SwissProt ID: | MBD3_HUMAN |
| Description: | methyl-CpG binding domain protein 3 [Source:HGNC Symbol;Acc:6918] |
| Location: | chr19 p13.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S56 | RYLGGsMDLST | MBD | PhosphoSitePlus; SysPTM |
| Y36 | RDVFYySPSGK | HPRD | |
| T61 | SMDLStFDFRT | MBD | PhosphoSitePlus |
| S56 | RYLGGsMDLST | HPRD; phosphoELM; SysPTM | |
| S85 | RVRYDsSNQVK | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| Y83 | RQRVRyDSSNQ | PhosphoSitePlus | |
| S24 | EVPRRsGLSAG | AURKA | HPRD |
| S24 | EVPRRsGLSAG | AurA | RegPhos |
| S144 | WEKKLsGLNAF | PhosphoSitePlus; HPRD | |
| Y35 | HRDVFyYSPSG | HPRD | |
| S37 | DVFYYsPSGKK | MBD | PhosphoSitePlus |
| S37 | DVFYYsPSGKK | HPRD | |
| S39 | FYYSPsGKKFR | MBD | PhosphoSitePlus |
| S86 | VRYDSsNQVKG | PhosphoSitePlus; HPRD; SysPTM | |
| S77 | SKMNKsRQRVR | PhosphoSitePlus; HPRD | |
| T66 | TFDFRtGKMLM | MBD | PhosphoSitePlus |
| S24 | EVPRRsGLSAG | Aurora A | phosphoELM |
| S24 | EVPRRsGLSAG | MBD | PhosphoSitePlus |
| Y35 | HRDVFyYSPSG | MBD | PhosphoSitePlus |
| Y36 | RDVFYySPSGK | MBD | PhosphoSitePlus |
| Dephosphorylation site |
| MBD3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| MBD3_HUMAN do not have mutation site. |
| Differential expressed protein |
| MBD3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| MBD3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| AURKA_HUMAN | MBD3_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| MBD3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0000792 | heterochromatin | IEA | cellular_component |
| GO:0043234 | protein complex | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0000785 | chromatin | IEA | cellular_component |
| GO:0016573 | histone acetylation | IEA | biological_process |
| GO:0016581 | NuRD complex | NAS | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006346 | methylation-dependent chromatin silencing | IEA | biological_process |
| GO:0009888 | tissue development | IEA | biological_process |
| GO:0005488 | binding | IEA | molecular_function |
| GO:0016581 | NuRD complex | IEA | cellular_component |
| GO:0000122 | negative regulation of transcription from RNA poly | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003682 | chromatin binding | IEA | molecular_function |
| GO:0001701 | in utero embryonic development | IEA | biological_process |