Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MAGI3_HUMAN
Description:membrane associated guanylate kinase, WW and PDZ domain containing 3 [Source:HGNC Symbol;Acc:29647]
Location:chr1 p13.2
Node attribute:PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S225RKRTTsVSKMEPhosphoSitePlus
Y116KDLRHyLSLQFPhosphoSitePlus
T147TIPCTtRAPRDGuanylate_kinPhosphoSitePlus
S235ERMDSsLPEEEPhosphoSitePlus
S1282RDQSLsPSKGEPhosphoSitePlus
T224QRKRTtSVSKMPhosphoSitePlus
S1284QSLSPsKGENKPhosphoSitePlus
S118LRHYLsLQFQKPhosphoSitePlus
S1280RPRDQsLSPSKPhosphoSitePlus
S234MERMDsSLPEEPhosphoSitePlus
T102PIRLKtVKPGKPhosphoSitePlus
S1059RGFGFsLRGGKPDZPhosphoSitePlus
S595FAIADsPTGQKHPRD
Y875APQEPyDVVLQPhosphoSitePlus

Dephosphorylation site
MAGI3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000358628T929ICOSMICSkin Cancer21984974
ENSP00000358628R766PCOSMICHead and Neck Cancer21798893
ENSP00000358628L897VCOSMICOvarian Cancer21720365
ENSP00000358628R768LCOSMICCentral Nervous System Neoplasms18772396
ENSP00000358628G946ECOSMICOvarian Cancer21720365
ENSP00000358624D892HBIOMARTBreast Cancer21930507, 21930502
ENSP00000358628Q529*COSMICLung Cancer20668451
ENSP00000358628K7RCOSMICLung Cancer20668451
ENSP00000358628D892HBIOMARTBreast Cancer21930507, 21930502
ENSP00000358628G737ACOSMICOvarian Cancer21720365
ENSP00000358628R808WCOSMICLung Cancer20668451

Differential expressed protein
MAGI3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MAGI3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MAGI3_HUMANPTEN_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04530Tight junction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005524ATP bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0006915apoptotic processNASbiological_process
GO:0005911cell-cell junctionIEAcellular_component
GO:0019048virus-host interactionIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0016020membraneNAScellular_component
GO:0005634nucleusIEAcellular_component
GO:0005923tight junctionIEAcellular_component
GO:0035556intracellular signal transductionNASbiological_process
GO:0004385guanylate kinase activityNASmolecular_function
GO:0043507positive regulation of JUN kinase activityIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0005109frizzled bindingIEAmolecular_function


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