Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MAGD1_HUMAN
Description:melanoma antigen family D, 1 [Source:HGNC Symbol;Acc:6813]
Location:chrX p11.22
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S643SYHETsKMKVLMAGEPhosphoSitePlus
S457PNSRAsQNPGAPhosphoSitePlus
T160VGPNAtYNFSQPhosphoSitePlus
S129AAYDFsQAATTPhosphoSitePlus
Y630SNPPEyEFLWGMAGEPhosphoSitePlus
Y126GPNAAyDFSQAPhosphoSitePlus
Y92GPNGVyDFSQAPhosphoSitePlus; HPRD; phosphoELM
T312GWQNQtARQTPPhosphoSitePlus
T85VQNATtKGPNGPhosphoSitePlus
Y481NKLVKyLMLKDMAGEPhosphoSitePlus
T274PLAAGtWRSAPPhosphoSitePlus
S638LWGLRsYHETSMAGEPhosphoSitePlus
Y148GPNGVyDFSQAHPRD
T642RSYHEtSKMKVMAGEPhosphoSitePlus
S95GVYDFsQAHNAPhosphoSitePlus
Y161GPNATyNFSQSPhosphoSitePlus

Dephosphorylation site
MAGD1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000364874S76ABIOMARTBreast Cancer21930507, 21930502
ENSP00000364927S76ABIOMARTBreast Cancer21930507, 21930502
ENSP00000364847S132ABIOMARTBreast Cancer21930507, 21930502
ENSP00000364847K131*COSMICOvarian Cancer21720365
ENSP00000364847W783*COSMICHead and Neck Cancer21798893
ENSP00000325333S76ABIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000325333Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
MAGD1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FAK2_HUMANMAGD1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
MAGD1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005886plasma membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0043065positive regulation of apoptotic processIEAbiological_process
GO:0042981regulation of apoptotic processTASbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0006357regulation of transcription from RNA polymerase IIIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentTASbiological_process
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0050680negative regulation of epithelial cell proliferatiIDAbiological_process
GO:0006915apoptotic processTASbiological_process
GO:0003713transcription coactivator activityIEAmolecular_function
GO:0090190positive regulation of branching involved in ureteIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0043406positive regulation of MAP kinase activityIEAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0043234protein complexIDAcellular_component


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