| UniProt/SwissProt ID: | MAFA_HUMAN |
| Description: | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) [Source:HGNC Symbol;Acc:23145] |
| Location: | chr8 q24.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S336 | FPREPsPPQAG | PhosphoSitePlus | |
| T134 | EALNLtPEDAV | Maf_N; Zip | PhosphoSitePlus |
| S14 | AELPSsPLAIE | MAPK1 | HPRD |
| S65 | SSVPSsPSFCA | PhosphoSitePlus | |
| S14 | AELPSsPLAIE | PhosphoSitePlus | |
| S14 | AELPSsPLAIE | MAPK14 | HPRD |
| S49 | RLPPGsLSSTP | PhosphoSitePlus | |
| T57 | STPLStPCSSV | PhosphoSitePlus | |
| S65 | SSVPSsPSFCA | MAPK1 | HPRD |
| T53 | GSLSStPLSTP | PhosphoSitePlus | |
| S61 | STPCSsVPSSP | PhosphoSitePlus | |
| Dephosphorylation site |
| MAFA_HUMAN do not have dephosphorylation site. |
| Mutation site |
| MAFA_HUMAN do not have mutation site. |
| Differential expressed protein |
| MAFA_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| MAFA_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MK01_HUMAN | MAFA_HUMAN | kinase -> substrate | HPRD |
| MK14_HUMAN | MAFA_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04930 | Type II diabetes mellitus |
| hsa04950 | Maturity onset diabetes of the young |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0030073 | insulin secretion | IDA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | TAS | molecular_function |
| GO:0042803 | protein homodimerization activity | TAS | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | TAS | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IEA | biological_process |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0009749 | response to glucose stimulus | IDA | biological_process |
| GO:0007263 | nitric oxide mediated signal transduction | IDA | biological_process |
| GO:0046982 | protein heterodimerization activity | NAS | molecular_function |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0045944 | positive regulation of transcription from RNA poly | IEA | biological_process |