Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:LUZP1_HUMAN
Description:leucine zipper protein 1 [Source:HGNC Symbol;Acc:14985]
Location:chr1 p36.12
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T676AKLVNtTITPEHPRD; phosphoELM
S932RRDLKsLEDPPPhosphoSitePlus
S108TRELKsEIERLHPRD
S570GALASsRRSSSPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S512TTRTFsDTTHGPhosphoSitePlus
S840SNHVSsPFELSPhosphoSitePlus; HPRD; phosphoELM
S949VESTNsNAYTQPhosphoSitePlus
S946GKNVEsTNSNAPhosphoSitePlus
S423NRQVSsPSFTNPhosphoSitePlus; HPRD; phosphoELM
S59AEGSNsSMLAECortBP2PhosphoSitePlus
Y1036CTLSVyRQLHNPhosphoSitePlus
S233YTRNAsNLERNPhosphoSitePlus; HPRD; SysPTM
T677KLVNTtITPEPPhosphoSitePlus; HPRD; phosphoELM
S574SSRRSsSEGLSPhosphoSitePlus; HPRD; phosphoELM
T938LEDPPtRIGKNPhosphoSitePlus
S804YPSDSsSPRAAHPRD
S440SHMGVsTDSGTHPRD
S575SRRSSsEGLSKPhosphoSitePlus
T821ERHTStSNIQVPhosphoSitePlus
T1004VSEVLtRRNRVHPRD
S957YTQRSsTDFSEPhosphoSitePlus; HPRD
S579SSEGLsKGKKAPhosphoSitePlus
S611PYSCRsQENILPhosphoSitePlus; HPRD
Y263KGGLDyLKQVEPhosphoSitePlus
S820RERHTsTSNIQPhosphoSitePlus; HPRD; phosphoELM
T777SGTETtLEKQKPhosphoSitePlus
S805PSDSSsPRAAPPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S690KPQPNsREKAKPhosphoSitePlus; HPRD; phosphoELM
T514RTFSDtTHGSVPhosphoSitePlus
T515TFSDTtHGSVPPhosphoSitePlus
S415NNENYsLSNRQPhosphoSitePlus
S1046NSLDPsELPGKPhosphoSitePlus
S822RHTSTsNIQVGPhosphoSitePlus
S995SRRTQsSLTVSPhosphoSitePlus; HPRD; SysPTM
S845SPFELsIHKHDPhosphoSitePlus
T953NSNAYtQRSSTPhosphoSitePlus
T819LRERHtSTSNIPhosphoSitePlus
Y799SSITIyPSDSSPhosphoSitePlus; HPRD
T727RASTNtMELPDPhosphoSitePlus
T510EKTTRtFSDTTPhosphoSitePlus; HPRD
S550VLGNGsQVTQAPhosphoSitePlus
S394TARELsPQHKRPhosphoSitePlus; HPRD; phosphoELM
S608SKYPYsCRSQEPhosphoSitePlus
S620ILQGFsTSHKEHPRD
S639VMEDSsPHEALPhosphoSitePlus; HPRD; phosphoELM
S1042RQLHNsLDPSEPhosphoSitePlus; HPRD
S338NKLLAsQLEEIPhosphoSitePlus; HPRD; phosphoELM
S659REKPDsDDDLDPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S801ITIYPsDSSSPPhosphoSitePlus; HPRD
S425QVSSPsFTNRRHPRD
T679VNTTItPEPEPPhosphoSitePlus; HPRD; phosphoELM
T993PSSRRtQSSLTPhosphoSitePlus; HPRD
S908SHSAPsEVGFSPhosphoSitePlus
T898APPAEtIRWKSPhosphoSitePlus
Y952TNSNAyTQRSSPhosphoSitePlus
S573ASSRRsSSEGLPhosphoSitePlus; HPRD
S108TRELKsEIERLCortBP2PhosphoSitePlus
Y607LSKYPySCRSQPhosphoSitePlus
S839VSNHVsSPFELPhosphoSitePlus; HPRD
S794PNKVTsSITIYPhosphoSitePlus
S996RRTQSsLTVSEPhosphoSitePlus; HPRD
S745SQRPFsPREALPhosphoSitePlus; HPRD
S956AYTQRsSTDFSPhosphoSitePlus; HPRD; phosphoELM
S905RWKSHsAPSEVPhosphoSitePlus; phosphoELM
S417ENYSLsNRQVSPhosphoSitePlus
Y414LNNENySLSNRPhosphoSitePlus
T702RGAPRtSLFENHPRD; phosphoELM
T958TQRSStDFSELPhosphoSitePlus; HPRD
S703GAPRTsLFENDPhosphoSitePlus; HPRD; phosphoELM
S803IYPSDsSSPRAPhosphoSitePlus; HPRD

Dephosphorylation site
LUZP1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000393460E1027KBIOMARTBreast Cancer21930507, 21930502
ENSP00000363752N36SCOSMICHead and Neck Cancer21798893
ENSP00000363752E1027KBIOMARTBreast Cancer21930507, 21930502
ENSP00000363752P682SCOSMICHead and Neck Cancer21984974
ENSP00000303758E1027KBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
LUZP1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
LUZP1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KS6A4_HUMANLUZP1_HUMANkinase -> substrateRobert H Newman (2013)
FGFR2_HUMANLUZP1_HUMANkinase -> substrateRobert H Newman (2013)
NEK3_HUMANLUZP1_HUMANkinase -> substrateRobert H Newman (2013)
TRIB3_HUMANLUZP1_HUMANkinase -> substrateRobert H Newman (2013)
AAPK2_HUMANLUZP1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
LUZP1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0060840artery developmentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0021503neural fold bendingIEAbiological_process
GO:0003281ventricular septum developmentIEAbiological_process