Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:LTBP1_HUMAN
Description:latent transforming growth factor beta binding protein 1 [Source:HGNC Symbol;Acc:6714]
Location:chr2 p22.3
Node attribute:PPI(target); PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y1600DFSEQyTPEADPhosphoSitePlus
Y1599VDFSEqYTPEAHPRD
Y1273VDFSEqYTPEAHPRD
T1601FSEQYtPEADPPhosphoSitePlus
S1596DALVDfSEQYTHPRD
T1600DFSEQyTPEADHPRD
Y1688NTDGSyKCLCLEGF_CAPhosphoSitePlus
Y904ICYEGyRFSEQEGF; EGF_CAPhosphoSitePlus
T897LPVRYtCICYEEGF_CAPhosphoSitePlus
Y523QSQVSyQGLPVEGF_CAPhosphoSitePlus
T991SGYRMtQRGRCEGF_CAPhosphoSitePlus
T531LPVQKtQTIHSEGF_CAPhosphoSitePlus
Y901YTCICyEGYRFEGF; EGF_CAPhosphoSitePlus
S1413VPAGEsSSEAGTBPhosphoSitePlus
S1597ALVDFsEQYTPPhosphoSitePlus
T1274DFSEQyTPEADHPRD
S1270DALVDfSEQYTHPRD
Y896NLPVRyTCICYEGF; EGF_CAPhosphoSitePlus

Dephosphorylation site
LTBP1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000384091D1245NTCGAOvarian Cancer21720365, 18772890
ENSP00000346467T213ABIOMARTPancreatic Cancer21930507, 21930502
ENSP00000386043A1574PBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000346467A1575PBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000386043T213ABIOMARTPancreatic Cancer21930507, 21930502
ENSP00000384091G1229ETCGAOvarian Cancer21720365, 18772890
ENSP00000385359A1195PBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000384091A1248PBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000374653A1249PBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
LTBP1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
LTBP1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
COMP_HUMANLTBP1_HUMANotherKEGG
LTBP1_HUMANTGFB1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04350TGF-beta signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0031012extracellular matrixIDAcellular_component
GO:0035583sequestering of TGFbeta in extracellular matrixTASbiological_process
GO:0019838growth factor bindingIEAmolecular_function
GO:0005578proteinaceous extracellular matrixNAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0005509calcium ion bindingIEAmolecular_function
GO:0005578proteinaceous extracellular matrixIEAcellular_component
GO:0005024transforming growth factor beta-activated receptorNASmolecular_function


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