Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:LRRC7_HUMAN
Description:leucine rich repeat containing 7 [Source:HGNC Symbol;Acc:18531]
Location:chr1 p31.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S1439TKGQRsMDGYPCaMK2aRegPhos
Y1210YSTESyGASQTPhosphoSitePlus
T865SKLETtPTTSPRegPhos
T348SCKNVtVMSLRLRR_4PhosphoSitePlus
Y234LKMLVyLDMSKLRR_4PhosphoSitePlus
T602ENSNPtANTEQPhosphoSitePlus
Y1205LSARSySTESYPhosphoSitePlus
S949FKKSQsIDEIDRegPhos
S933STERLsPLMKDRegPhos
Y52TLEELyLDANQLRR_4PhosphoSitePlus
S850WTRTPsPFEDRRegPhos
S1163VTVTEsQFLKRPhosphoSitePlus
Y572RYPTPyPEDLKPhosphoSitePlus
S1439TKGQRsMDGYPRegPhos
S1439TKGQRsMDGYPCAMK2AHPRD
T1370PPDTItKKAGSPhosphoSitePlus
S90PTTIAsLVNLKRegPhos
S708RVKVGsLQTTAPhosphoSitePlus; HPRD
T570LKRYPtPYPEDPhosphoSitePlus
T856PFEDRtAFPSKPhosphoSitePlus
S351NVTVMsLRSNKLRR_4PhosphoSitePlus
S1491PDGPAsNLLQPPDZPhosphoSitePlus
T411LIPLQtEAHPEHPRD
S343PREIGsCKNVTPhosphoSitePlus
T1161SSVTVtESQFLPhosphoSitePlus
T1368DVPPDtITKKAPhosphoSitePlus
T711VGSLQtTAKDAHPRD
S1156GLDRQsSVTVTPhosphoSitePlus
T1215YGASQtRPVSAPhosphoSitePlus
Y1179DEHPSyQEVKAPhosphoSitePlus

Dephosphorylation site
LRRC7_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000035383V1364ECOSMICOvarian Cancer21720365
ENSP00000035383A1021STCGAOvarian Cancer21720365, 18772890
ENSP00000035383R353CBIOMARTBreast Cancer21930507, 21930502
ENSP00000035383P1496HTCGAOvarian Cancer21720365, 18772890
ENSP00000035383R703PCOSMICOvarian Cancer21720365
ENSP00000035383L235MSjoblom2006, COSMIC, HPIBreast Cancer16959974
ENSP00000035383R703PTCGAOvarian Cancer21720365, 18772890
ENSP00000035383D938HTCGAOvarian Cancer21720365, 18772890
ENSP00000035383Y687*BIOMARTBreast Cancer21930507, 21930502
ENSP00000035383A1021SCOSMICOvarian Cancer21720365
ENSP00000309245T870NBIOMARTBreast Cancer21930507, 21930502
ENSP00000035383R72GCOSMICOvarian Cancer21720365
ENSP00000035383G1344ECOSMICSkin Cancer21984974
ENSP00000035383D938HCOSMICOvarian Cancer21720365
ENSP00000309245S35CBIOMARTBreast Cancer21930507, 21930502
ENSP00000035383N719KTCGAOvarian Cancer21720365, 18772890
ENSP00000035383S1204TCOSMICHead and Neck Cancer21798893
ENSP00000035383D1141NCOSMICOvarian Cancer20826764
ENSP00000035383S30CBIOMARTBreast Cancer21930507, 21930502
ENSP00000035383N719KCOSMICOvarian Cancer21720365
ENSP00000035383T865NBIOMARTBreast Cancer21930507, 21930502
ENSP00000035383A413VCOSMICHead and Neck Cancer21984974
ENSP00000309245Y692*BIOMARTBreast Cancer21930507, 21930502
ENSP00000035383V1364ETCGAOvarian Cancer21720365, 18772890
ENSP00000035383Q1326ECOSMICHead and Neck Cancer21798893
ENSP00000309245R358CBIOMARTBreast Cancer21930507, 21930502
ENSP00000035383P1496HCOSMICOvarian Cancer21720365
ENSP00000035383G1497RCOSMICHepatocellular Carcinoma
ENSP00000035383N240fs*3COSMICBreast Cancer16959974
ENSP00000035383S1063TCOSMICCentral Nervous System Neoplasms18772396

Differential expressed protein
LRRC7_HUMAN is not differential expressed protein.

Hyperphosphorylation site
LRRC7_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KCC2A_HUMANLRRC7_HUMANkinase -> substrateHPRD
ZAGL2_HUMANLRRC7_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
LRRC7_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0014069postsynaptic densityIEAcellular_component
GO:0045211postsynaptic membraneIEAcellular_component
GO:0030054cell junctionIEAcellular_component
GO:0005886plasma membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component