Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:LIME1_HUMAN
Description:Lck interacting transmembrane adaptor 1 [Source:HGNC Symbol;Acc:26016]
Location:chr20 q13.33
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y200QVDVLySRVCKPhosphoSitePlus; HPRD; phosphoELM; RegPhos
Y145GLEATySNVGLPhosphoSitePlus; RegPhos
Y254PLENVyESIRELCKRegPhos
S256ENVYEsIRELGPhosphoSitePlus
Y235AGDLAyQTLPLPhosphoSitePlus; RegPhos
S95ALRPAsMDLLRPhosphoSitePlus
Y254PLENVyESIREPhosphoSitePlus
S201VDVLYsRVCKPPhosphoSitePlus; HPRD
Y167PVVAEyARVQKPhosphoSitePlus; HPRD; RegPhos

Dephosphorylation site
LIME1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000309521Q114*COSMICHepatocellular Carcinoma21822264

Differential expressed protein
LIME1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
LIME1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
LCK_HUMANLIME1_HUMANkinase -> substrateRegPhos; NetPath
LYN_HUMANLIME1_HUMANkinase -> substrateNetPath
ZAGL2_HUMANLIME1_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
LIME1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0051279regulation of release of sequestered calcium ion iIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0070851growth factor receptor bindingIEAmolecular_function
GO:0019815B cell receptor complexIEAcellular_component
GO:0043122regulation of I-kappaB kinase/NF-kappaB cascadeIEAbiological_process
GO:0043405regulation of MAP kinase activityIEAbiological_process
GO:0006357regulation of transcription from RNA polymerase IIIEAbiological_process
GO:0014066regulation of phosphatidylinositol 3-kinase cascadIEAbiological_process
GO:0050853B cell receptor signaling pathwayIEAbiological_process
GO:0019901protein kinase bindingIEAmolecular_function
GO:0050852T cell receptor signaling pathwayIEAbiological_process
GO:0042345regulation of NF-kappaB import into nucleusIEAbiological_process


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