| UniProt/SwissProt ID: | KLF1_HUMAN |
| Description: | Kruppel-like factor 1 (erythroid) [Source:HGNC Symbol;Acc:6345] |
| Location: | chr19 p13.2 |
| Node attribute: | substrate; TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T23 | GPFPDtQDDFL | CK2_group | phosphoELM; RegPhos |
| T304 | HLRTHtGEKPY | PhosphoSitePlus | |
| T15 | SISTLtALGPF | PhosphoSitePlus | |
| T302 | KAHLRtHTGEK | zf-C2H2 | PhosphoSitePlus |
| T23 | GPFPDtQDDFL | PRKACA | HPRD |
| T23 | GPFPDtQDDFL | PKACa | RegPhos |
| Dephosphorylation site |
| KLF1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| KLF1_HUMAN do not have mutation site. |
| Differential expressed protein |
| KLF1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| KLF1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCA_HUMAN | KLF1_HUMAN | kinase -> substrate | HPRD |
| KLF1_HUMAN | HBB_HUMAN | TF -> target gene | TRANSFAC |
| KLF1_HUMAN | HBG2_HUMAN | TF -> target gene | TRANSFAC |
| KLF1_HUMAN | HBG1_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| KLF1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006338 | chromatin remodeling | IEA | biological_process |
| GO:0030218 | erythrocyte differentiation | IMP | biological_process |
| GO:0035162 | embryonic hemopoiesis | IEA | biological_process |
| GO:0043249 | erythrocyte maturation | IEA | biological_process |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0001889 | liver development | IEA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | TAS | molecular_function |
| GO:0048821 | erythrocyte development | IEA | biological_process |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0001701 | in utero embryonic development | IEA | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0000987 | core promoter proximal region sequence-specific DN | IDA | molecular_function |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IDA | biological_process |
| GO:0000790 | nuclear chromatin | IDA | cellular_component |
| GO:0044212 | transcription regulatory region DNA binding | IDA | molecular_function |