Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KLF12_HUMAN
Description:Kruppel-like factor 12 [Source:HGNC Symbol;Acc:6346]
Location:chr13 q22.1
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S240QSKSDsDDDDLPhosphoSitePlus
T104SPVSMtASASSPhosphoSitePlus
S202YTAVRsPGNVNPhosphoSitePlus
S117STSTSsSSSSRPhosphoSitePlus
S102SSSPVsMTASAPhosphoSitePlus
T15IKNINtFENRMPhosphoSitePlus
T249DLPNVtLDSVNPhosphoSitePlus
T340KAHRRtHTGEKzf-C2H2PhosphoSitePlus
S119STSSSsSSRLAPhosphoSitePlus
S273QEVHPsPVSRVPhosphoSitePlus
S92NKARTsPTAVSPhosphoSitePlus
T342HRRTHtGEKPYPhosphoSitePlus
T91INKARtSPTAVPhosphoSitePlus
S109TASASsPSSTSPhosphoSitePlus
S99TAVSSsPVSMTPhosphoSitePlus

Dephosphorylation site
KLF12_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000366897P166LCOSMICSkin Cancer21984974
ENSP00000366897K335ECOSMICOvarian Cancer21720365

Differential expressed protein
KLF12_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KLF12_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KLF12_HUMANAP2A_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KLF12_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIDAbiological_process
GO:0005622intracellularIEAcellular_component
GO:0003714transcription corepressor activityTASmolecular_function
GO:0003677DNA bindingIDAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0003700sequence-specific DNA binding transcription factorIDAmolecular_function
GO:0006357regulation of transcription from RNA polymerase IITASbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0008270zinc ion bindingIEAmolecular_function


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