Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KLF11_HUMAN
Description:Kruppel-like factor 11 [Source:HGNC Symbol;Acc:11811]
Location:chr2 p25.1
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T447SRHRRtHTGEKzf-H2C2_2PhosphoSitePlus
T83SGDVTtTVHMDPhosphoSitePlus
S124TRTPVsPQVTDPhosphoSitePlus
T82DSGDVtTTVHMPhosphoSitePlus
S150VARALsGGAERPhosphoSitePlus
T449HRRTHtGEKKFzf-H2C2_2PhosphoSitePlus
T419HLRTHtGEKPFzf-H2C2_2PhosphoSitePlus
S166EPVPSsPCRAKPhosphoSitePlus
S111ITPPQsPDLVEPhosphoSitePlus
T417KAHLRtHTGEKzf-H2C2_2PhosphoSitePlus
T73RIRPLtPVSDSPhosphoSitePlus

Dephosphorylation site
KLF11_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000307023C21YCOSMICOvarian Cancer21720365
ENSP00000442722C4YTCGAOvarian Cancer21720365, 18772890
ENSP00000307023K63NCOSMICOvarian Cancer21720365
ENSP00000444690C4YTCGAOvarian Cancer21720365, 18772890
ENSP00000307023Q126*COSMICHead and Neck Cancer21798893

Differential expressed protein
KLF11_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KLF11_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KLF11_HUMANHBB_HUMANTF -> target geneTRANSFAC
KLF11_HUMANHBG2_HUMANTF -> target geneTRANSFAC
KLF11_HUMANHBE_HUMANTF -> target geneTRANSFAC
KLF11_HUMANHBG1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KLF11_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0044212transcription regulatory region DNA bindingIDAmolecular_function
GO:0006915apoptotic processIEAbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0000115regulation of transcription involved in S phase ofIDAbiological_process
GO:0000981sequence-specific DNA binding RNA polymerase II trIDAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0000122negative regulation of transcription from RNA polyIDAbiological_process
GO:0005622intracellularIEAcellular_component
GO:0008285negative regulation of cell proliferationIDAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0043065positive regulation of apoptotic processIDAbiological_process


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