Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KI3L1_HUMAN
Description:killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 [Source:HGNC Symbol;Acc:6338]
Location:chr19 q13.42
Node attribute:receptor; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S385NRTANsEDSDEPhosphoSitePlus
S296YRCFGsFRHSPCDK3HPRD
S246TLSCSsRSSYDigPhosphoSitePlus
S415KITRPsQRPKTPhosphoSitePlus
T420SQRPKtPPTDTPhosphoSitePlus
S388ANSEDsDEQDPPhosphoSitePlus

Dephosphorylation site
KI3L1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000375608F150IBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000375608P230LBIOMARTBreast Cancer21930507, 21930502
ENSP00000375608V315GBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
KI3L1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KI3L1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
1B82_HUMANKI3L1_HUMANligand -> receptorHPMR
CDK3_HUMANKI3L1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04612Antigen processing and presentation
hsa04612Antigen processing and presentation
hsa05332Graft-versus-host disease
hsa04650Natural killer cell mediated cytotoxicity
hsa04650Natural killer cell mediated cytotoxicity
hsa05332Graft-versus-host disease

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030109HLA-B specific inhibitory MHC class I receptor actNASmolecular_function
GO:0050776regulation of immune responseTASbiological_process
GO:0005887integral to plasma membraneNAScellular_component
GO:0005886plasma membraneTAScellular_component
GO:0006955immune responseNASbiological_process


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