| UniProt/SwissProt ID: | KI3L1_HUMAN |
| Description: | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 [Source:HGNC Symbol;Acc:6338] |
| Location: | chr19 q13.42 |
| Node attribute: | receptor; substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S385 | NRTANsEDSDE | PhosphoSitePlus | |
| S296 | YRCFGsFRHSP | CDK3 | HPRD |
| S246 | TLSCSsRSSYD | ig | PhosphoSitePlus |
| S415 | KITRPsQRPKT | PhosphoSitePlus | |
| T420 | SQRPKtPPTDT | PhosphoSitePlus | |
| S388 | ANSEDsDEQDP | PhosphoSitePlus | |
| Dephosphorylation site |
| KI3L1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000375608 | F150I | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000375608 | P230L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000375608 | V315G | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| KI3L1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| KI3L1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| 1B82_HUMAN | KI3L1_HUMAN | ligand -> receptor | HPMR |
| CDK3_HUMAN | KI3L1_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04612 | Antigen processing and presentation |
| hsa04612 | Antigen processing and presentation |
| hsa05332 | Graft-versus-host disease |
| hsa04650 | Natural killer cell mediated cytotoxicity |
| hsa04650 | Natural killer cell mediated cytotoxicity |
| hsa05332 | Graft-versus-host disease |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0030109 | HLA-B specific inhibitory MHC class I receptor act | NAS | molecular_function |
| GO:0050776 | regulation of immune response | TAS | biological_process |
| GO:0005887 | integral to plasma membrane | NAS | cellular_component |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0006955 | immune response | NAS | biological_process |