| UniProt/SwissProt ID: | KCIP4_HUMAN |
| Description: | Kv channel interacting protein 4 [Source:HGNC Symbol;Acc:30083] |
| Location: | chr4 p15.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y168 | WAFNLyDINKD | efhand | PhosphoSitePlus |
| Y91 | ELQILyRGFKN | PhosphoSitePlus | |
| Dephosphorylation site |
| KCIP4_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000371585 | Q67H | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000399080 | Q54H | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000371583 | *226Y | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| KCIP4_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| KCIP4_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PKN1_HUMAN | KCIP4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| FAK2_HUMAN | KCIP4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| KCIP4_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005244 | voltage-gated ion channel activity | IEA | molecular_function |
| GO:0043025 | neuronal cell body | IEA | cellular_component |
| GO:0005267 | potassium channel activity | IEA | molecular_function |
| GO:0005578 | proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0005509 | calcium ion binding | IEA | molecular_function |
| GO:0030425 | dendrite | IEA | cellular_component |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0007165 | signal transduction | IEA | biological_process |