Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KC1AL_HUMAN
Description:casein kinase 1, alpha 1-like [Source:HGNC Symbol;Acc:20289]
Location:chr13 q13.3
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S206RDDMEsLGYVFPkinase_CK1PhosphoSitePlus
Y59HPQLLyESKLYPkinase_CK1PhosphoSitePlus
Y294NHQYDyTFDWTPhosphoSitePlus
Y209MESLGyVFMYFPkinase_CK1PhosphoSitePlus
T287RILFRtLNHQYPhosphoSitePlus
T228GLRAMtKKQKYPkinase_CK1PhosphoSitePlus
Y292TLNHQyDYTFDPhosphoSitePlus
Y213GYVFMyFNRTSPkinase_CK1PhosphoSitePlus
T184KHLIGtVRYASPkinase_CK1PhosphoSitePlus

Dephosphorylation site
KC1AL_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000369126R21QBIOMART, HPIColorectal Cancer21930507, 21930502, 16959974
ENSP00000369126E10KBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000369126H75LBIOMARTBreast Cancer21930507, 21930502
ENSP00000369126R21QSjoblom2006Intestines Cancer16959974, 21930507, 21930502

Differential expressed protein
KC1AL_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KC1AL_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KC1AL_HUMANGLI1_HUMANkinase -> substrateKEGG
KC1AL_HUMANASAP3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04340Hedgehog signaling pathway
hsa04310Wnt signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIEAcellular_component
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0030529ribonucleoprotein complexIEAcellular_component
GO:0005524ATP bindingIEAmolecular_function
GO:0016055Wnt receptor signaling pathwayIEAbiological_process
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0000902cell morphogenesisIEAbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0004672protein kinase activityIEAmolecular_function


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23