| UniProt/SwissProt ID: | JADE1_HUMAN |
| Description: | PHD finger protein 17 [Source:HGNC Symbol;Acc:30027] |
| Location: | chr4 q28.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S812 | VEMSDsESEAS | PhosphoSitePlus | |
| T739 | AVKVPtTPASP | PhosphoSitePlus | |
| T92 | PVSPGtIPQPV | HPRD; phosphoELM | |
| S89 | VQVPVsPGTIP | HPRD; phosphoELM | |
| T740 | VKVPTtPASPV | PhosphoSitePlus | |
| S796 | KSKLKsDNEND | PhosphoSitePlus | |
| S603 | DPLQNsPGSEG | PhosphoSitePlus; HPRD | |
| T713 | QSAPGtRKEIV | PhosphoSitePlus | |
| S9 | GRLPSsSEDSD | PhosphoSitePlus | |
| S13 | SSSEDsDDNGS | PhosphoSitePlus | |
| T827 | IHTSStISRRT | HPRD | |
| S392 | GAPECsPRNPL | PhosphoSitePlus; HPRD | |
| S10 | RLPSSsEDSDD | PhosphoSitePlus | |
| Y507 | VRNLTyMVTRR | Glyco_hydro_57; NuA4 | PhosphoSitePlus |
| S703 | TRAATsPGVGQ | PhosphoSitePlus | |
| S709 | PGVGQsAPGTR | PhosphoSitePlus | |
| S8 | RGRLPsSSEDS | PhosphoSitePlus | |
| S743 | PTTPAsPVKNW | PhosphoSitePlus; HPRD | |
| S89 | VQVPVsPGTIP | EPL1 | PhosphoSitePlus |
| T702 | NTRAAtSPGVG | PhosphoSitePlus | |
| S810 | PDVEMsDSESE | PhosphoSitePlus | |
| S606 | QNSPGsEGKTL | PhosphoSitePlus | |
| Y803 | NENDGyVPDVE | PhosphoSitePlus | |
| T92 | PVSPGtIPQPV | EPL1 | PhosphoSitePlus |
| T610 | GSEGKtLLKQP | PhosphoSitePlus | |
| Dephosphorylation site |
| JADE1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000226319 | C182R | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| JADE1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| JADE1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MK01_HUMAN | JADE1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| SNRK_HUMAN | JADE1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KPCB_HUMAN | JADE1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KPCA_HUMAN | JADE1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| JADE1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0006950 | response to stress | NAS | biological_process |
| GO:0006915 | apoptotic process | NAS | biological_process |
| GO:0043981 | histone H4-K5 acetylation | IDA | biological_process |
| GO:0000123 | histone acetyltransferase complex | IDA | cellular_component |
| GO:0043982 | histone H4-K8 acetylation | IDA | biological_process |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0030308 | negative regulation of cell growth | NAS | biological_process |
| GO:0043966 | histone H3 acetylation | IDA | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0005739 | mitochondrion | IDA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0043983 | histone H4-K12 acetylation | IDA | biological_process |