Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ITAX_HUMAN
Description:integrin, alpha X (complement component 3 receptor 4 subunit) [Source:HGNC Symbol;Acc:6152]
Location:chr16 p11.2
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S673SRDLQsSVTLDPhosphoSitePlus
S668KNLLGsRDLQSPhosphoSitePlus
S674RDLQSsVTLDLPhosphoSitePlus

Dephosphorylation site
ITAX_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000268296W501*COSMICSkin Cancer21984974
ENSP00000268296A412VCOSMICPancreatic Cancer21252315
ENSP00000268296K535QCOSMICOvarian Cancer21720365
ENSP00000268296K535QTCGAOvarian Cancer21720365, 18772890
ENSP00000268296S885FCOSMICSkin Cancer21984974
ENSP00000268296A176VCOSMICHead and Neck Cancer21798893
ENSP00000268296L1051FBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
ITAX_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ITAX_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
JUN_HUMANITAX_HUMANTF -> target geneTRANSFAC
ETS1_HUMANITAX_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
ITAX_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007155cell adhesionIEAbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0007229integrin-mediated signaling pathwayIEAbiological_process
GO:0051607defense response to virusIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0009887organ morphogenesisTASbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0050900leukocyte migrationTASbiological_process
GO:0008305integrin complexIEAcellular_component
GO:0004872receptor activityTASmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0009897external side of plasma membraneIEAcellular_component


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