Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IRK11_HUMAN
Description:potassium inwardly-rectifying channel, subfamily J, member 11 [Source:HGNC Symbol;Acc:6257]
Location:chr11 p15.1
Node attribute:effector

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T224VVRKTtSPEGEIRKPhosphoSitePlus
Y26PAEPRyRARQRPhosphoSitePlus
T180HRRAEtLIFSKIRKPhosphoSitePlus
S208GDLRKsMIISAIRKPhosphoSitePlus

Dephosphorylation site
IRK11_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000345708A178TCOSMICSkin Cancer21984974

Differential expressed protein
IRK11_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IRK11_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GBG12_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBB2_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBG1_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBG3_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBG8_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBB1_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBG2_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBG10_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBG11_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBB3_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBG13_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBG5_HUMANIRK11_HUMANGprotein -> effectorgpDB
GBB5_HUMANIRK11_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04930Type II diabetes mellitus

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0071805potassium ion transmembrane transportIDAbiological_process
GO:0030955potassium ion bindingTASmolecular_function
GO:0005739mitochondrionIEAcellular_component
GO:0015272ATP-activated inward rectifier potassium channel aIEAmolecular_function
GO:0010107potassium ion importIEAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0005783endoplasmic reticulumIEAcellular_component
GO:0050877neurological system processIMPbiological_process
GO:0006006glucose metabolic processIMPbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0044325ion channel bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0050796regulation of insulin secretionIMPbiological_process
GO:0006112energy reserve metabolic processTASbiological_process
GO:0042391regulation of membrane potentialIDAbiological_process
GO:0046676negative regulation of insulin secretionIMPbiological_process
GO:0008076voltage-gated potassium channel complexIDAcellular_component
GO:0005887integral to plasma membraneTAScellular_component
GO:0030315T-tubuleIEAcellular_component
GO:0043231intracellular membrane-bounded organelleIEAcellular_component
GO:0005242inward rectifier potassium channel activityIEAmolecular_function
GO:0042383sarcolemmaIEAcellular_component
GO:0006813potassium ion transportIEAbiological_process
GO:0033198response to ATPIDAbiological_process
GO:0031072heat shock protein bindingIEAmolecular_function
GO:0008282ATP-sensitive potassium channel complexIEAcellular_component
GO:0005886plasma membraneIDAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0033574response to testosterone stimulusIEAbiological_process
GO:0007268synaptic transmissionTASbiological_process
GO:0030506ankyrin bindingIEAmolecular_function
GO:0044281small molecule metabolic processTASbiological_process
GO:0008022protein C-terminus bindingIEAmolecular_function
GO:0005249voltage-gated potassium channel activityIDAmolecular_function


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