Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IRK10_HUMAN
Description:potassium inwardly-rectifying channel, subfamily J, member 10 [Source:HGNC Symbol;Acc:6256]
Location:chr1 q23.2
Node attribute:effector

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T32RRRVLtKDGRSIRKPhosphoSitePlus

Dephosphorylation site
IRK10_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000357068S328RCOSMICOvarian Cancer21720365

Differential expressed protein
IRK10_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IRK10_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GBG2_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBB2_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBG12_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBG5_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBG11_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBB1_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBG10_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBB3_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBG1_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBG13_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBB5_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBG8_HUMANIRK10_HUMANGprotein -> effectorgpDB
GBG3_HUMANIRK10_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04971Gastric acid secretion

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005887integral to plasma membraneTAScellular_component
GO:0006954inflammatory responseIEAbiological_process
GO:0007601visual perceptionIEAbiological_process
GO:0007628adult walking behaviorIEAbiological_process
GO:0051384response to glucocorticoid stimulusIEAbiological_process
GO:0010107potassium ion importIEAbiological_process
GO:0048169regulation of long-term neuronal synaptic plasticiIEAbiological_process
GO:0051930regulation of sensory perception of painIEAbiological_process
GO:0022010central nervous system myelinationIEAbiological_process
GO:0009637response to blue lightIEAbiological_process
GO:0006813potassium ion transportTASbiological_process
GO:0005242inward rectifier potassium channel activityIEAmolecular_function
GO:0005267potassium channel activityIEAmolecular_function
GO:0051935L-glutamate uptake involved in synaptic transmissiIEAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0042391regulation of membrane potentialIEAbiological_process
GO:0006813potassium ion transportIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0051385response to mineralocorticoid stimulusIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0071805potassium ion transmembrane transportIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0016010dystrophin-associated glycoprotein complexIEAcellular_component
GO:0051938L-glutamate importIEAbiological_process
GO:0016323basolateral plasma membraneIEAcellular_component
GO:0016324apical plasma membraneIEAcellular_component
GO:0014003oligodendrocyte developmentIEAbiological_process
GO:0005902microvillusIEAcellular_component
GO:0021554optic nerve developmentIEAbiological_process
GO:0055075potassium ion homeostasisIEAbiological_process
GO:0051289protein homotetramerizationIEAbiological_process
GO:0015272ATP-activated inward rectifier potassium channel aTASmolecular_function
GO:0005886plasma membraneIEAcellular_component
GO:0060075regulation of resting membrane potentialIEAbiological_process
GO:0060081membrane hyperpolarizationIEAbiological_process
GO:0042802identical protein bindingIEAmolecular_function
GO:0007268synaptic transmissionTASbiological_process


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