| UniProt/SwissProt ID: | IRF9_HUMAN |
| Description: | interferon regulatory factor 9 [Source:HGNC Symbol;Acc:6131] |
| Location: | chr14 q12 |
| Node attribute: | TF |
| Phosphorylation site |
| IRF9_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| IRF9_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000380073 | Q123K | COSMIC | Skin Cancer | 21984974 | ENSP00000380073 | N227K | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000380073 | R142S | COSMIC | Ovarian Cancer | 21720365 | ENSP00000380073 | R142S | TCGA | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| IRF9_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| IRF9_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| IRF9_HUMAN | ISG15_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| IRF9_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0045351 | type I interferon biosynthetic process | IEA | biological_process |
| GO:0007166 | cell surface receptor signaling pathway | TAS | biological_process |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0051607 | defense response to virus | IEA | biological_process |
| GO:0060333 | interferon-gamma-mediated signaling pathway | TAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0060337 | type I interferon-mediated signaling pathway | TAS | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0000975 | regulatory region DNA binding | IEA | molecular_function |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0019221 | cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0005634 | nucleus | TAS | cellular_component |
| GO:0006366 | transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |