Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IRF4_HUMAN
Description:interferon regulatory factor 4 [Source:HGNC Symbol;Acc:6119]
Location:chr6 p25.3
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y325APDGLyAKRLCPhosphoSitePlus
Y428HFLRGyDLPEHPhosphoSitePlus
Y37IDSGKyPGLVWIRFPhosphoSitePlus
Y192HPEIPyQCPMTPhosphoSitePlus; HPRD
Y125DPYKVyRIVPEIRFPhosphoSitePlus
Y440SNPEDyHRSIRPhosphoSitePlus
Y122DISDPyKVYRIIRFPhosphoSitePlus

Dephosphorylation site
IRF4_HUMAN do not have dephosphorylation site.

Mutation site
IRF4_HUMAN do not have mutation site.

Differential expressed protein
IRF4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IRF4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
IRF4_HUMANIL4_HUMANTF -> target geneTRANSFAC
IRF4_HUMANISG15_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
IRF4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIDAcellular_component
GO:0000788nuclear nucleosomeIEAcellular_component
GO:0045086positive regulation of interleukin-2 biosynthetic IDAbiological_process
GO:0072540T-helper 17 cell lineage commitmentISSbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0034122negative regulation of toll-like receptor signalinIEAbiological_process
GO:0045082positive regulation of interleukin-10 biosyntheticIDAbiological_process
GO:0043565sequence-specific DNA bindingISSmolecular_function
GO:0045368positive regulation of interleukin-13 biosyntheticIDAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0043966histone H3 acetylationIEAbiological_process
GO:0045404positive regulation of interleukin-4 biosynthetic IDAbiological_process
GO:0019221cytokine-mediated signaling pathwayTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0060333interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0042832defense response to protozoanISSbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0043967histone H4 acetylationIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorISSmolecular_function
GO:0008134transcription factor bindingNASmolecular_function
GO:0005829cytosolTAScellular_component
GO:0043388positive regulation of DNA bindingIEAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0060337type I interferon-mediated signaling pathwayTASbiological_process
GO:0000975regulatory region DNA bindingIEAmolecular_function
GO:0045622regulation of T-helper cell differentiationNASbiological_process
GO:0043011myeloid dendritic cell differentiationIEAbiological_process
GO:0042110T cell activationNASbiological_process


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