| UniProt/SwissProt ID: | IL3_HUMAN |
| Description: | interleukin 3 (colony-stimulating factor, multiple) [Source:HGNC Symbol;Acc:6011] |
| Location: | chr5 q31.1 |
| Node attribute: | gene |
| Phosphorylation site |
| IL3_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| IL3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000296870 | P16L | COSMIC | Central Nervous System Neoplasms | 18772396 |
| Differential expressed protein |
| IL3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| IL3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PO2F1_HUMAN | IL3_HUMAN | TF -> target gene | TRANSFAC |
| VEZF1_HUMAN | IL3_HUMAN | TF -> target gene | TRANSFAC |
| RUNX1_HUMAN | IL3_HUMAN | TF -> target gene | TRANSFAC |
| NFAC2_HUMAN | IL3_HUMAN | TF -> target gene | TRANSFAC |
| EGR1_HUMAN | IL3_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| IL3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0042523 | positive regulation of tyrosine phosphorylation of | IDA | biological_process |
| GO:0006955 | immune response | IEA | biological_process |
| GO:0005135 | interleukin-3 receptor binding | TAS | molecular_function |
| GO:0008284 | positive regulation of cell proliferation | ISS | biological_process |
| GO:0008083 | growth factor activity | IEA | molecular_function |
| GO:0005615 | extracellular space | ISS | cellular_component |
| GO:0035162 | embryonic hemopoiesis | IDA | biological_process |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphory | ISS | biological_process |
| GO:0007267 | cell-cell signaling | TAS | biological_process |
| GO:0045740 | positive regulation of DNA replication | IDA | biological_process |
| GO:0007399 | nervous system development | TAS | biological_process |
| GO:0005125 | cytokine activity | IEA | molecular_function |
| GO:0005576 | extracellular region | TAS | cellular_component |