| UniProt/SwissProt ID: | IGSF5_HUMAN |
| Description: | immunoglobulin superfamily, member 5 [Source:HGNC Symbol;Acc:5952] |
| Location: | chr21 q22.2 |
| Node attribute: | substrate; PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T233 | ATVNLtVIRCP | PhosphoSitePlus | |
| Dephosphorylation site |
| IGSF5_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000369962 | V267A | COSMIC | Skin Cancer | 21984974 | ENSP00000369962 | D350E | BIOMART | Gastric Cancer | 21930507, 21930502 |
| Differential expressed protein |
| IGSF5_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| IGSF5_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCA_HUMAN | IGSF5_HUMAN | kinase -> substrate | KEGG |
| PP2AA_HUMAN | IGSF5_HUMAN | phosphatase -> substrate | KEGG |
| PARD3_HUMAN | IGSF5_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04530 | Tight junction |
| hsa05120 | Epithelial cell signaling in Helicobacter pylori i |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016337 | cell-cell adhesion | IEA | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0009986 | cell surface | IEA | cellular_component |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005923 | tight junction | IEA | cellular_component |