Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IFNG_HUMAN
Description:interferon, gamma [Source:HGNC Symbol;Acc:5438]
Location:chr12 q15
Node attribute:PPI(source); gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y6MKYTSyILAFQPhosphoSitePlus
Y22GSLGCyCQDPYIFN-gammaPhosphoSitePlus

Dephosphorylation site
IFNG_HUMAN do not have dephosphorylation site.

Mutation site
IFNG_HUMAN do not have mutation site.

Differential expressed protein
IFNG_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IFNG_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
IFNG_HUMANSMAD6_HUMANotherKEGG
AP2A_HUMANIFNG_HUMANTF -> target geneTRANSFAC
TYY1_HUMANIFNG_HUMANTF -> target geneTRANSFAC
SP1_HUMANIFNG_HUMANTF -> target geneTRANSFAC
TF65_HUMANIFNG_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05332Graft-versus-host disease
hsa04660T cell receptor signaling pathway
hsa05144Malaria
hsa05140Leishmaniasis
hsa05330Allograft rejection
hsa05146Amoebiasis
hsa04140Regulation of autophagy
hsa05164Influenza A
hsa03050Proteasome
hsa05168Herpes simplex infection
hsa04380Osteoclast differentiation
hsa05142Chagas disease (American trypanosomiasis)
hsa05145Toxoplasmosis
hsa04350TGF-beta signaling pathway
hsa04650Natural killer cell mediated cytotoxicity
hsa05132Salmonella infection
hsa04940Type I diabetes mellitus
hsa05143African trypanosomiasis
hsa05162Measles
hsa04630Jak-STAT signaling pathway
hsa05323Rheumatoid arthritis
hsa05322Systemic lupus erythematosus
hsa04612Antigen processing and presentation
hsa04060Cytokine-cytokine receptor interaction
hsa05152Tuberculosis
hsa05169Epstein-Barr virus infection

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0050796regulation of insulin secretionIDAbiological_process
GO:0000122negative regulation of transcription from RNA polyISSbiological_process
GO:0031642negative regulation of myelinationIEAbiological_process
GO:0071351cellular response to interleukin-18IEAbiological_process
GO:0033141positive regulation of peptidyl-serine phosphorylaIDAbiological_process
GO:0032747positive regulation of interleukin-23 productionIDAbiological_process
GO:0002026regulation of the force of heart contractionIEAbiological_process
GO:0003340negative regulation of mesenchymal to epithelial tIEAbiological_process
GO:0032735positive regulation of interleukin-12 productionIEAbiological_process
GO:0044146negative regulation of growth of symbiont involvedIEAbiological_process
GO:0009615response to virusIDAbiological_process
GO:0009897external side of plasma membraneIEAcellular_component
GO:0000060protein import into nucleus, translocationIDAbiological_process
GO:0071222cellular response to lipopolysaccharideIEAbiological_process
GO:0060550positive regulation of fructose 1,6-bisphosphate 1IDAbiological_process
GO:0008285negative regulation of cell proliferationIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0045666positive regulation of neuron differentiationIEAbiological_process
GO:0034393positive regulation of smooth muscle cell apoptotiIDAbiological_process
GO:0060333interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0003340negative regulation of mesenchymal to epithelial tISSbiological_process
GO:0072308negative regulation of metanephric nephron tubule ISSbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0002250adaptive immune responseIEAbiological_process
GO:0045672positive regulation of osteoclast differentiationIDAbiological_process
GO:0006915apoptotic processIGIbiological_process
GO:0060557positive regulation of vitamin D biosynthetic procIDAbiological_process
GO:0045429positive regulation of nitric oxide biosynthetic pIDAbiological_process
GO:0048304positive regulation of isotype switching to IgG isIEAbiological_process
GO:0045348positive regulation of MHC class II biosynthetic pIEAbiological_process
GO:0002302CD8-positive, alpha-beta T cell differentiation inIEAbiological_process
GO:0002053positive regulation of mesenchymal cell proliferatISSbiological_process
GO:0045429positive regulation of nitric oxide biosynthetic pIEAbiological_process
GO:0045410positive regulation of interleukin-6 biosynthetic IEAbiological_process
GO:0042832defense response to protozoanIEAbiological_process
GO:0042511positive regulation of tyrosine phosphorylation ofIEAbiological_process
GO:0042742defense response to bacteriumIEAbiological_process
GO:0007050cell cycle arrestIDAbiological_process
GO:0006955immune responseIEAbiological_process
GO:0032700negative regulation of interleukin-17 productionIDAbiological_process
GO:0019882antigen processing and presentationIEAbiological_process
GO:0050776regulation of immune responseIEAbiological_process
GO:0006928cellular component movementTASbiological_process
GO:0032760positive regulation of tumor necrosis factor produIEAbiological_process
GO:0060559positive regulation of calcidiol 1-monooxygenase aIDAbiological_process
GO:2000309positive regulation of tumor necrosis factor (ligaIDAbiological_process
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0032735positive regulation of interleukin-12 productionIDAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0005576extracellular regionIDAcellular_component
GO:0032224positive regulation of synaptic transmission, cholIEAbiological_process
GO:0045785positive regulation of cell adhesionIEAbiological_process
GO:0045084positive regulation of interleukin-12 biosyntheticIEAbiological_process
GO:0072308negative regulation of metanephric nephron tubule IEAbiological_process
GO:0033141positive regulation of peptidyl-serine phosphorylaIEAbiological_process
GO:0042102positive regulation of T cell proliferationIEAbiological_process
GO:0051712positive regulation of killing of cells of other oIDAbiological_process
GO:0006959humoral immune responseIEAbiological_process
GO:0045080positive regulation of chemokine biosynthetic procIEAbiological_process
GO:0005133interferon-gamma receptor bindingIEAmolecular_function
GO:0002053positive regulation of mesenchymal cell proliferatIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0006925inflammatory cell apoptotic processIEAbiological_process
GO:0051044positive regulation of membrane protein ectodomainIDAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0050718positive regulation of interleukin-1 beta secretioIEAbiological_process
GO:0060552positive regulation of fructose 1,6-bisphosphate mIDAbiological_process
GO:0048662negative regulation of smooth muscle cell proliferIDAbiological_process
GO:0060334regulation of interferon-gamma-mediated signaling TASbiological_process
GO:0005125cytokine activityIEAmolecular_function
GO:0030593neutrophil chemotaxisIEAbiological_process
GO:0019221cytokine-mediated signaling pathwayTASbiological_process
GO:0044130negative regulation of growth of symbiont in hostIEAbiological_process
GO:0051607defense response to virusIEAbiological_process
GO:0042511positive regulation of tyrosine phosphorylation ofIDAbiological_process
GO:0001781neutrophil apoptotic processIEAbiological_process
GO:0030968endoplasmic reticulum unfolded protein responseIEAbiological_process