Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ID3_HUMAN
Description:inhibitor of DNA binding 3, dominant negative helix-loop-helix protein [Source:HGNC Symbol;Acc:5362]
Location:chr1 p36.12
Node attribute:ubiquitination(target); substrate; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S5MKALSpVRGCCDK2RegPhos; SysPTM
S21CLSERsLAIARPhosphoSitePlus
S5VRGCHPRD; SysPTM
S5_MKALsPVRGCPhosphoSitePlus; SysPTM
S18AVCCLsERSLAPhosphoSitePlus
Y11PVRGCyEAVCCPhosphoSitePlus
S5VRGCCDK2HPRD; phosphoELM; SysPTM

Dephosphorylation site
ID3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000363689P95SCOSMICCentral Nervous System Neoplasms18772890

Differential expressed protein
ID3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ID3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANID3_HUMANkinase -> substrateNetPath
CDK2_HUMANID3_HUMANkinase -> substrateHPRD; RegPhos; NetPath
SMUF2_HUMANID3_HUMANubiquitinationNetPath
PRDM1_HUMANID3_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04350TGF-beta signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005634nucleusIEAcellular_component
GO:0030903notochord developmentIEAbiological_process
GO:0001656metanephros developmentIEAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0007275multicellular organismal developmentTASbiological_process
GO:0007507heart developmentIEAbiological_process
GO:0043433negative regulation of sequence-specific DNA bindiIDAbiological_process
GO:0051726regulation of cell cycleIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0030182neuron differentiationIEAbiological_process
GO:0030855epithelial cell differentiationIEAbiological_process
GO:0008134transcription factor bindingIEAmolecular_function
GO:0006275regulation of DNA replicationIEAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0046983protein dimerization activityIEAmolecular_function
GO:0042476odontogenesisIEAbiological_process
GO:0019904protein domain specific bindingIEAmolecular_function
GO:0007417central nervous system developmentIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0003714transcription corepressor activityTASmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0043065positive regulation of apoptotic processIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0009611response to woundingIEAbiological_process
GO:0045668negative regulation of osteoblast differentiationIEAbiological_process


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