Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ICAM3_HUMAN
Description:intercellular adhesion molecule 3 [Source:HGNC Symbol;Acc:5346]
Location:chr19 p13.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T526VREEStYLPLTPhosphoSitePlus
S518HQRSGsYHVREPKCtRegPhos
S516REHQRsGSYHVPhosphoSitePlus; phosphoELM; RegPhos
S518HQRSGsYHVREPRKCQHPRD
S525HVREEsTYLPLPhosphoSitePlus; phosphoELM; RegPhos
S532YLPLTsMQPTEPhosphoSitePlus
T151PRTSLtVVLLRIg_2PhosphoSitePlus
S518HQRSGsYHVREPKCt(PKC thetaRegPhos
S518HQRSGsYHVREPhosphoSitePlus
T536TSMQPtEAMGEPhosphoSitePlus
Y527REESTyLPLTSPhosphoSitePlus
S518HQRSGsYHVREPKC_thetaphosphoELM
Y519QRSGSyHVREEPhosphoSitePlus

Dephosphorylation site
ICAM3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000160262P25SCOSMICOvarian Cancer21720365
ENSP00000160262H456LCOSMICHead and Neck Cancer

Differential expressed protein
ICAM3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ICAM3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCT_HUMANICAM3_HUMANkinase -> substrateHPRD; Robert H Newman (2013)
ZAGL2_HUMANICAM3_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04514Cell adhesion molecules (CAMs)

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005102receptor bindingTASmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0005178integrin bindingIPImolecular_function
GO:0016337cell-cell adhesionIEAbiological_process
GO:0050776regulation of immune responseTASbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0005886plasma membraneTAScellular_component
GO:0016020membraneIEAcellular_component


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