| UniProt/SwissProt ID: | ICAM3_HUMAN |
| Description: | intercellular adhesion molecule 3 [Source:HGNC Symbol;Acc:5346] |
| Location: | chr19 p13.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T526 | VREEStYLPLT | PhosphoSitePlus | |
| S518 | HQRSGsYHVRE | PKCt | RegPhos |
| S516 | REHQRsGSYHV | PhosphoSitePlus; phosphoELM; RegPhos | |
| S518 | HQRSGsYHVRE | PRKCQ | HPRD |
| S525 | HVREEsTYLPL | PhosphoSitePlus; phosphoELM; RegPhos | |
| S532 | YLPLTsMQPTE | PhosphoSitePlus | |
| T151 | PRTSLtVVLLR | Ig_2 | PhosphoSitePlus |
| S518 | HQRSGsYHVRE | PKCt(PKC theta | RegPhos |
| S518 | HQRSGsYHVRE | PhosphoSitePlus | |
| T536 | TSMQPtEAMGE | PhosphoSitePlus | |
| Y527 | REESTyLPLTS | PhosphoSitePlus | |
| S518 | HQRSGsYHVRE | PKC_theta | phosphoELM |
| Y519 | QRSGSyHVREE | PhosphoSitePlus | |
| Dephosphorylation site |
| ICAM3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000160262 | P25S | COSMIC | Ovarian Cancer | 21720365 | ENSP00000160262 | H456L | COSMIC | Head and Neck Cancer |
| Differential expressed protein |
| ICAM3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ICAM3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCT_HUMAN | ICAM3_HUMAN | kinase -> substrate | HPRD; Robert H Newman (2013) |
| ZAGL2_HUMAN | ICAM3_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04514 | Cell adhesion molecules (CAMs) |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005102 | receptor binding | TAS | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005178 | integrin binding | IPI | molecular_function |
| GO:0016337 | cell-cell adhesion | IEA | biological_process |
| GO:0050776 | regulation of immune response | TAS | biological_process |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0016020 | membrane | IEA | cellular_component |