| UniProt/SwissProt ID: | IAPP_HUMAN |
| Description: | islet amyloid polypeptide [Source:HGNC Symbol;Acc:5329] |
| Location: | chr12 p12.1 |
| Node attribute: | ligand |
| Phosphorylation site |
| IAPP_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| IAPP_HUMAN do not have dephosphorylation site. |
| Mutation site |
| IAPP_HUMAN do not have mutation site. |
| Differential expressed protein |
| IAPP_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| IAPP_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| IAPP_HUMAN | CALCR_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04950 | Maturity onset diabetes of the young |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0045779 | negative regulation of bone resorption | IEA | biological_process |
| GO:0045596 | negative regulation of cell differentiation | IEA | biological_process |
| GO:0019233 | sensory perception of pain | IEA | biological_process |
| GO:0005102 | receptor binding | TAS | molecular_function |
| GO:0005179 | hormone activity | IEA | molecular_function |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0031018 | endocrine pancreas development | TAS | biological_process |
| GO:0006915 | apoptotic process | TAS | biological_process |
| GO:0043025 | neuronal cell body | IEA | cellular_component |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0007267 | cell-cell signaling | TAS | biological_process |
| GO:0005615 | extracellular space | IEA | cellular_component |