Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:HXB4_HUMAN
Description:homeobox B4 [Source:HGNC Symbol;Acc:5115]
Location:chr17 q21.32
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S46GQRREsSFQPEPhosphoSitePlus
Y142KEPVVyPWMRKPhosphoSitePlus
S90PPPGLsPRAPAPhosphoSitePlus

Dephosphorylation site
HXB4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000328928A135TCOSMICOvarian Cancer21720365

Differential expressed protein
HXB4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
HXB4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
USF1_HUMANHXB4_HUMANTF -> target geneTRANSFAC
USF2_HUMANHXB4_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
HXB4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0009952anterior/posterior pattern specificationIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0060218hematopoietic stem cell differentiationIDAbiological_process
GO:0003700sequence-specific DNA binding transcription factorNASmolecular_function
GO:0006355regulation of transcription, DNA-dependentNASbiological_process
GO:0048539bone marrow developmentIEAbiological_process
GO:2000738positive regulation of stem cell differentiationIDAbiological_process
GO:0048705skeletal system morphogenesisIEAbiological_process
GO:0005634nucleusNAScellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0060216definitive hemopoiesisIEAbiological_process
GO:0048704embryonic skeletal system morphogenesisIEAbiological_process
GO:0008283cell proliferationIEAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0002011morphogenesis of an epithelial sheetIEAbiological_process
GO:0048536spleen developmentIEAbiological_process
GO:0007275multicellular organismal developmentNASbiological_process
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0030097hemopoiesisIEAbiological_process
GO:0048103somatic stem cell divisionIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process


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