Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:HSPB8_HUMAN
Description:heat shock 22kDa protein 8 [Source:HGNC Symbol;Acc:30171]
Location:chr12 q24.23
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S27RDSPLsSRLLDPhosphoSitePlus; SysPTM
T63SAWPGtLRSGMPKC_groupphosphoELM; RegPhos; SysPTM
T87PAEGRtPPPFPErk1(MAPK3RegPhos
S57ALPRLsSAWPGPhosphoSitePlus
S14SCHYPsRLRRDPKCaRegPhos
T63SAWPGtLRSGMPhosphoSitePlus; SysPTM
S27RDSPLsSRLLDMAPK3HPRD; phosphoELM; SysPTM
S104CVNVHsFKPEEHSP20; YabPPhosphoSitePlus
T87PAEGRtPPPFPErk1RegPhos
T63SAWPGtLRSGMPKCaRegPhos; SysPTM
S24DPFRDsPLSSRPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y118KTKDGyVEVSGHPRD; phosphoELM
S14SCHYPsRLRRDPhosphoSitePlus
S14SCHYPsRLRRDPRKCAHPRD
T87PAEGRtPPPFPMAPK3HPRD; phosphoELM
Y118KTKDGyVEVSGHSP20; YabPPhosphoSitePlus
S27RDSPLsSRLLDErk1(MAPK3RegPhos; SysPTM
T63SAWPGtLRSGMPRKCAHPRD; SysPTM
S27RDSPLsSRLLDErk1RegPhos; SysPTM
T87PAEGRtPPPFPPhosphoSitePlus
S14SCHYPsRLRRDPKC_groupphosphoELM; RegPhos

Dephosphorylation site
HSPB8_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000281938G67SGreenman2007Central Nervous System Neoplasms16618716, 17344846, 18428421
ENSP00000281938G67SGreenman2007, HPINeoplasms by Histologic Type16618716, 17344846, 18428421

Differential expressed protein
HSPB8_HUMAN is not differential expressed protein.

Hyperphosphorylation site
HSPB8_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANHSPB8_HUMANkinase -> substrateHPRD
MK03_HUMANHSPB8_HUMANkinase -> substrateHPRD; Robert H Newman (2013)

Function Annotation
KEGG Pathway
HSPB8_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0005622intracellularIDAcellular_component
GO:0008219cell deathIEAbiological_process
GO:0008150biological_processNDbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0006950response to stressIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0042802identical protein bindingIPImolecular_function


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