Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:HS71L_HUMAN
Description:heat shock 70kDa protein 1-like [Source:HGNC Symbol;Acc:5234]
Location:chrHSCHR6_MHC_DBB p2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S420LIKRNsTIPTKHSP70PhosphoSitePlus
Y117ENKAFyPEEISHPRD
Y547NALESyAFNMKHSP70PhosphoSitePlus
T464GRFDLtGIPPAHSP70PhosphoSitePlus
S256HKKDIsQNKRAHPRD
S122YPEEIsSMVLTHSP70PhosphoSitePlus
T224FEVKAtAGDTHHPRD
Y373DEAVAyGAAVQphosphoELM
T132TKLKEtAEAFLHPRD
S364RDLNKsINPDEHSP70PhosphoSitePlus
T127SSMVLtKLKETHSP70PhosphoSitePlus
T504KVNKItITNDKHSP70PhosphoSitePlus
S42NRTTPsYVAFTHSP70PhosphoSitePlus
S155AYFNDsQRQATHSP70PhosphoSitePlus
T68MNPQNtVFDAKHSP70PhosphoSitePlus
Y17DLGTTySCVGVHSP70PhosphoSitePlus
T68MNPQNtVFDAKHPRD
Y117ENKAFyPEEISHSP70PhosphoSitePlus
T179IINEPtAAAIAHSP70PhosphoSitePlus
Y43RTTPSyVAFTDHSP70PhosphoSitePlus
T132TKLKEtAEAFLHSP70PhosphoSitePlus
S256HKKDIsQNKRAHSP70PhosphoSitePlus
T300FYTSItRARFEHSP70PhosphoSitePlus
S123PEEISsMVLTKHSP70PhosphoSitePlus
T267VRRLRtACERAHSP70PhosphoSitePlus
S364RDLNKsINPDEHPRD; phosphoELM
T40QGNRTtPSYVAHSP70PhosphoSitePlus

Dephosphorylation site
HS71L_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000387691T224NCOSMICNeoplasms by Histologic Type
ENSP00000387691A548VCOSMICMelanoma21499247
ENSP00000364805A548VCOSMICMelanoma21499247
ENSP00000364805E270DCOSMICRenal Cancer20054297
ENSP00000387691E270DCOSMICRenal Cancer20054297
ENSP00000364805T224NCOSMICNeoplasms by Histologic Type
ENSP00000364805E246QCOSMICOvarian Cancer21720365
ENSP00000387691E246QCOSMICOvarian Cancer21720365
ENSP00000387691E516QCOSMICOvarian Cancer21720365
ENSP00000364805E516QCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000364805Oral CancerNormal vs. CancertissueDown0.3519297561

Hyperphosphorylation site
HS71L_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SCYL2_HUMANHS71L_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
HS71L_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000902cell morphogenesisIEAbiological_process
GO:0006986response to unfolded proteinTASbiological_process
GO:0005759mitochondrial matrixIEAcellular_component
GO:0008180signalosomeIDAcellular_component
GO:0005524ATP bindingIEAmolecular_function
GO:0005739mitochondrionIEAcellular_component


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