| UniProt/SwissProt ID: | HRH2_HUMAN |
| Description: | histamine receptor H2 [Source:HGNC Symbol;Acc:5183] |
| Location: | chr5 q35.2 |
| Node attribute: | receptor; GPCR |
| Phosphorylation site |
| HRH2_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| HRH2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| HRH2_HUMAN do not have mutation site. |
| Differential expressed protein |
| HRH2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| HRH2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HDC_HUMAN | HRH2_HUMAN | ligand -> receptor | HPMR |
| HRH2_HUMAN | GNAS1_HUMAN | GPCR -> Gprotein | gpDB |
| HRH2_HUMAN | GNAS2_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04971 | Gastric acid secretion |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04020 | Calcium signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007187 | G-protein coupled receptor signaling pathway, coup | TAS | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0006955 | immune response | TAS | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0004969 | histamine receptor activity | IEA | molecular_function |