Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:HNF6_HUMAN
Description:one cut homeobox 1 [Source:HGNC Symbol;Acc:8138]
Location:chr15 q21.3
Node attribute:substrate; TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y68SGGGDyHHHHRPhosphoSitePlus
T461SSSSStCTKA_PhosphoSitePlus
S455SNSGNsSSSSSPhosphoSitePlus
Y308TELKRySIPQACUTPhosphoSitePlus
Y168NLYTPyHKDVAPhosphoSitePlus
T326CRSQGtLSDLLCUTPhosphoSitePlus
S459NSSSSsSTCTKPhosphoSitePlus
S450QDEGSsNSGNSPhosphoSitePlus

Dephosphorylation site
HNF6_HUMAN do not have dephosphorylation site.

Mutation site
HNF6_HUMAN do not have mutation site.

Differential expressed protein
HNF6_HUMAN is not differential expressed protein.

Hyperphosphorylation site
HNF6_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NEK4_HUMANHNF6_HUMANkinase -> substrateRobert H Newman (2013)
HNF6_HUMANHNF4A_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
HNF6_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005634nucleusNAScellular_component
GO:0031018endocrine pancreas developmentTASbiological_process
GO:0001077RNA polymerase II core promoter proximal region seISSmolecular_function
GO:0045893positive regulation of transcription, DNA-dependenNASbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0006006glucose metabolic processIEAbiological_process
GO:0048536spleen developmentIEAbiological_process
GO:0002064epithelial cell developmentIEAbiological_process
GO:0042384cilium assemblyIEAbiological_process
GO:0006357regulation of transcription from RNA polymerase IIIEAbiological_process
GO:0030154cell differentiationIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentNASbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0030335positive regulation of cell migrationIEAbiological_process
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0045944positive regulation of transcription from RNA polyISSbiological_process
GO:0031016pancreas developmentIEAbiological_process
GO:0031018endocrine pancreas developmentIEAbiological_process
GO:0030512negative regulation of transforming growth factor IEAbiological_process
GO:0045165cell fate commitmentIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0030183B cell differentiationIEAbiological_process
GO:0007492endoderm developmentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0009653anatomical structure morphogenesisIEAbiological_process
GO:0001889liver developmentIEAbiological_process
GO:0001952regulation of cell-matrix adhesionIEAbiological_process


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