Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:HMOX2_HUMAN
Description:heme oxygenase (decycling) 2 [Source:HGNC Symbol;Acc:5014]
Location:chr16 p13.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T286SCPFRtAMAVLPhosphoSitePlus
S79LYFTYsALEEECSNK2A1HPRD
Y157HAYTRyMGDLSHeme_oxygenasePhosphoSitePlus
Y202QFKQLyRARMNHeme_oxygenasePhosphoSitePlus

Dephosphorylation site
HMOX2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000219700R205SCOSMICSkin Cancer21984974
ENSP00000219700D112NCOSMICHead and Neck Cancer21798893

Differential expressed protein
HMOX2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
HMOX2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK21_HUMANHMOX2_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04978Mineral absorption
hsa00860Porphyrin and chlorophyll metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005789endoplasmic reticulum membraneTAScellular_component
GO:0055114oxidation-reduction processIEAbiological_process
GO:0006879cellular iron ion homeostasisTASbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0006979response to oxidative stressIEAbiological_process
GO:0006778porphyrin-containing compound metabolic processTASbiological_process
GO:0001666response to hypoxiaIDAbiological_process
GO:0004392heme oxygenase (decyclizing) activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0042167heme catabolic processTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0006788heme oxidationIEAbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0055085transmembrane transportTASbiological_process


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