| UniProt/SwissProt ID: | HMGN3_HUMAN |
| Description: | high mobility group nucleosomal binding domain 3 [Source:HGNC Symbol;Acc:12312] |
| Location: | chr6 q14.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S57 | PGAKIsRGAKG | HMG14_17 | PhosphoSitePlus |
| T10 | KSPENtEGKDG | HPRD; phosphoELM; SysPTM | |
| S93 | AQKTEsVDNEG | HMG14_17 | PhosphoSitePlus; SysPTM |
| T83 | SENGEtKAEEA | HPRD; phosphoELM | |
| S31 | RSARLsAKPAP | HMG14_17 | PhosphoSitePlus |
| S31 | RSARLsAKPAP | HPRD | |
| T10 | KSPENtEGKDG | HMG14_17 | PhosphoSitePlus; SysPTM |
| S78 | EGTAPsENGET | HPRD; phosphoELM | |
| S93 | AQKTEsVDNE | HPRD; phosphoELM; SysPTM | |
| T83 | SENGEtKAEEA | HMG14_17 | PhosphoSitePlus |
| S27 | EPTRRsARLSA | HPRD | |
| T91 | EEAQKtESVDN | HPRD; phosphoELM | |
| S27 | EPTRRsARLSA | HMG14_17 | PhosphoSitePlus |
| S78 | EGTAPsENGET | HMG14_17 | PhosphoSitePlus |
| S6 | ENTE | HPRD | |
| S6 | MPKRKsPENTE | HMG14_17 | PhosphoSitePlus |
| Dephosphorylation site |
| HMGN3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000275036 | *78Y | COSMIC | Hepatocellular Carcinoma | 21822264 |
| Differential expressed protein |
| HMGN3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| HMGN3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK9_HUMAN | HMGN3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| HMGN3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003682 | chromatin binding | IEA | molecular_function |
| GO:0045944 | positive regulation of transcription from RNA poly | IEA | biological_process |
| GO:0061178 | regulation of insulin secretion involved in cellul | IEA | biological_process |
| GO:0031492 | nucleosomal DNA binding | IEA | molecular_function |
| GO:0000785 | chromatin | IEA | cellular_component |
| GO:0005634 | nucleus | NAS | cellular_component |
| GO:0008150 | biological_process | ND | biological_process |
| GO:0046966 | thyroid hormone receptor binding | NAS | molecular_function |
| GO:0016568 | chromatin modification | IEA | biological_process |
| GO:0051091 | positive regulation of sequence-specific DNA bindi | IEA | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |