Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:H2B1K_HUMAN
Description:histone cluster 1, H2bk [Source:HGNC Symbol;Acc:13954]
Location:chr6 p22.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S33KKRKRsRKESYHistonePhosphoSitePlus
S15APKKGsKKAVTMST1(STK4RegPhos
T116AVSEGtKAVTKPhosphoSitePlus
Y84SRLAHyNKRSTHistonePhosphoSitePlus
S88HYNKRsTITSRHistonePhosphoSitePlus
T89YNKRStITSREHistonePhosphoSitePlus
S124VTKYTsAK___PhosphoSitePlus
S113AKHAVsEGTKAPhosphoSitePlus
S39RKESYsVYVYKHistonePhosphoSitePlus
Y43YSVYVyKVLKQHistonePhosphoSitePlus
S37RSRKEsYSVYVHistonePhosphoSitePlus
T120GTKAVtKYTSAPhosphoSitePlus
T53QVHPDtGISSKHistonePhosphoSitePlus
S57DTGISsKAMGIHistonePhosphoSitePlus
Y41ESYSVyVYKVLHistonePhosphoSitePlus
S56PDTGIsSKAMGHistonePhosphoSitePlus
S65MGIMNsFVNDIHistonePhosphoSitePlus
T91KRSTItSREIQHistonePhosphoSitePlus
Y38SRKESySVYVYHistonePhosphoSitePlus

Dephosphorylation site
H2B1K_HUMAN do not have dephosphorylation site.

Mutation site
H2B1K_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000380100Gastric CancerTreatment (none vs. drug-resistant)cell lineDown0.6220625496

Hyperphosphorylation site
H2B1K_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
STK4_HUMANH2B1K_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05034Alcoholism
hsa05203Viral carcinogenesis
hsa05322Systemic lupus erythematosus

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0005622intracellularIEAcellular_component
GO:0006334nucleosome assemblyIEAbiological_process
GO:0046982protein heterodimerization activityIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0042742defense response to bacteriumIEAbiological_process
GO:0000786nucleosomeIEAcellular_component


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