| UniProt/SwissProt ID: | GPVI_HUMAN |
| Description: | glycoprotein VI (platelet) [Source:HGNC Symbol;Acc:14388] |
| Location: | chrHSCHR19LRC_COX1_C |
| Node attribute: | PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y67 | LSSSRyQDQAV | PhosphoSitePlus | |
| Dephosphorylation site |
| GPVI_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000334552 | P233A | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000394922 | P251A | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000394922 | R301Q | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 | ENSP00000308782 | P251A | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000394922 | R319Q | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
| Differential expressed protein |
| GPVI_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| GPVI_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CO1A1_HUMAN | GPVI_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04512 | ECM-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007596 | blood coagulation | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0004872 | receptor activity | TAS | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005887 | integral to plasma membrane | IEA | cellular_component |
| GO:0007167 | enzyme linked receptor protein signaling pathway | TAS | biological_process |
| GO:0030168 | platelet activation | NAS | biological_process |
| GO:0005518 | collagen binding | IEA | molecular_function |
| GO:0004888 | transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0005518 | collagen binding | TAS | molecular_function |
| GO:0050900 | leukocyte migration | TAS | biological_process |