Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GNDS_HUMAN
Description:ral guanine nucleotide dissociation stimulator [Source:HGNC Symbol;Acc:9842]
Location:chr9 q34.2
Node attribute:PPI(source); PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T767SSASTtPVAATPhosphoSitePlus
Y586MKDYLyGRLINHPRD
S821SILVTsQDKAPRAPhosphoSitePlus
T820KSILVtSQDKARAPhosphoSitePlus
S816GNMYKsILVTSRAPhosphoSitePlus
S745ESASQsSPETSPhosphoSitePlus
Y531MKDYLyGRLINHPRD
S753ETSGIsSASSSPhosphoSitePlus
T542TSKFAtLEMNPRasGEFPhosphoSitePlus
Y584TAMKDyLYGRLRasGEFPhosphoSitePlus
S741KKFWEsASQSSPhosphoSitePlus

Dephosphorylation site
GNDS_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000361120R496LSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000361120R496LHPIColorectal Cancer16959974
ENSP00000361120R114WCOSMICLung Cancer20668451

Differential expressed protein
GNDS_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GNDS_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GNDS_HUMANRHOA_HUMANotherKEGG
RASK_HUMANGNDS_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05200Pathways in cancer
hsa05212Pancreatic cancer
hsa05210Colorectal cancer

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005829cytosolTAScellular_component
GO:0005083small GTPase regulator activityIDAmolecular_function
GO:0007265Ras protein signal transductionTASbiological_process
GO:0005622intracellularIEAcellular_component
GO:0051056regulation of small GTPase mediated signal transduIEAbiological_process
GO:0005085guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0007165signal transductionIEAbiological_process
GO:0007264small GTPase mediated signal transductionIEAbiological_process


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