| UniProt/SwissProt ID: | GIPR_HUMAN |
| Description: | gastric inhibitory polypeptide receptor [Source:HGNC Symbol;Acc:4271] |
| Location: | chr19 q13.32 |
| Node attribute: | GPCR; receptor; PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S381 | FEIFLsSFQGF | 7tm_2; TM | PhosphoSitePlus |
| S382 | EIFLSsFQGFL | 7tm_2; TM | PhosphoSitePlus |
| Dephosphorylation site |
| GIPR_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000263281 | L206F | COSMIC | Melanoma | 21499247 |
| Differential expressed protein |
| GIPR_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| GIPR_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GIP_HUMAN | GIPR_HUMAN | ligand -> receptor | HPMR |
| GIPR_HUMAN | GNAS1_HUMAN | GPCR -> Gprotein | gpDB |
| GIPR_HUMAN | GNAS2_HUMAN | GPCR -> Gprotein | gpDB |
| GLHA_HUMAN | GIPR_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016519 | gastric inhibitory peptide receptor activity | IEA | molecular_function |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0004888 | transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0007166 | cell surface receptor signaling pathway | TAS | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0007584 | response to nutrient | TAS | biological_process |
| GO:0007190 | activation of adenylate cyclase activity | TAS | biological_process |
| GO:0006091 | generation of precursor metabolites and energy | TAS | biological_process |